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Gated voltammetry

  • US 8,404,100 B2
  • Filed: 02/26/2008
  • Issued: 03/26/2013
  • Est. Priority Date: 09/30/2005
  • Status: Active Grant
First Claim
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1. In an electrochemical method for determining the concentration of an analyte in a sample, where the method includes applying an input signal to a sensor strip so the analyte undergoes a redox reaction to generate an electric current that is measured and correlated with the concentration of the analyte in the sample,the sensor strip including electrodes and reagents, where the reagents include an oxidoreductase and react with and transfer electrons from the analyte to the electrodes;

  • the improvement comprising applying a gated voltammetric pulse sequence to the sample comprising at least two duty cycles, where each of the duty cycles includes an excitation and a relaxation, the relaxation is from 0.1 to 3 seconds, and the relaxation includes a current reduction to one-half or less of the current flow at the excitation maxima.

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