Ion acceleration system for medical and/or other applications

• US 8,405,056 B2
• Filed: 12/28/2006
• Issued: 03/26/2013
• Est. Priority Date: 12/28/2006
• Status: Active Grant

• Current Assignee: Advanced Oncotherapy Plc
• Original Assignee: Fondazione Per Adroterapia Oncologica- Tera
• Inventors: Amaldi, Ugo, Braccini, Saverio, Magrin, Giulio, Pearce, Peter, Zennaro, Riccardo
• Primary Examiner(s): Mondt, Johannes P
• Application Number:
  US12/521,724
• Publication Number:
  US 20100320403A1
• Time in Patent Office: 2,280 Days
• Field of Search: None
• US Class Current: 250/505.1
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/10 X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy A61N5/01 takes precedence
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries
• CPC Class Codes: G21K 5/04 with beam-forming means
• CPC Class Codes: G21K 5/10 with provision for relative movement of beam source and object to be irradiated
• CPC Class Codes: H05H 7/22 Details of linear accelerators, e.g. drift tubes H05H7/02 - H05H7/20 take precedence
• CPC Class Codes: H05H 9/00 Linear accelerators

Abstract

The ion acceleration system or complex (T) for medical and/or other applications is composed in essence by an ion source (1), a pre-accelerator (3) and one or more linear accelerators or linacs (6, 8, 10, 13), at least one of which is mounted on a rotating mechanical gantry-like structure (17). The isocentrical gantry (17) is equipped with a beam delivery system, which can be either ‘active’ or ‘passive’, for medical and/or other applications. The ion source (1) and the pre-accelerator (3) can be either installed on the floor, which is connected with the gantry basement, or mounted, fully or partially, on the rotating mechanical structure (17). The output beam can vary in energy and intensity pulse-by-pulse by adjusting the radio-frequency field in the accelerating modules of the linac(s) and the beam parameters at the input of the linear accelerators.

Claims

1. An acceleration system for charged nuclear particles with mass number equal or greater than 1, comprising:

a rotating mechanical gantry structure;

at least one radiofrequency (RF) linear accelerator configured for producing a pulsed ion beam,

said accelerator comprising at least one linac section mounted on the rotating gantry structure, the accelerator configured for rotating around an axis to irradiate a target or patient from more than one direction with the produced pulsed ion beam, the produced pulsed ion beam configured for treating a patient tumor or malformation; and

radio-frequency (RF) power generators located outside the rotating gantry structure and connected to the at least one linac section via rotating wave-guide devices.

2. A system for ion acceleration according to claim 1, further comprising:

an ion source producing an ion beam; and

a particle accelerator, configured as pre-accelerator to impart energy to particles within the ion beam, produced by the ion source, before injecting the ion beam into the at least one linac section mounted on the rotating gantry structure.

3. A system for ion acceleration according to claim 2, wherein the pre-accelerator is another linac section.

4. A system for ion acceleration according to claim 2, wherein the pre-accelerator is a cyclotron.

5. A system for ion acceleration according to claim 1, a system for ion beam delivery mounted on the rotating gantry structure.

6. A system for ion acceleration according to claim 1, wherein,

the at least one linac section comprises plural linac sections, and

each linac section is configured to run at a different frequency.

7. A system for ion acceleration according to claim 1, wherein,

the linac section comprises plural successive accelerating modules mounted on the rotating gantry structure, and

output energy of the pulsed ion beam is modulated by varying an input (RF) power to each of the successive accelerating modules which constitute the linac section.

8. A system for ion acceleration according to claim 1, wherein the pulsed ion beam is made of protons.

9. A system for ion acceleration according to claim 8, wherein the pulsed ion beam further is made of carbon ions.

10. A system for ion acceleration according to claim 1, wherein the pulsed ion beam comprises 230 MeV protons.

11. A method of producing radiopharmaceuticals, comprising a step of producing a pulsed ion beam using the system of claim 1.

12. A method of providing cancer radiation therapy, comprising the step of producing a pulsed ion beam using the system of claim 1.

13. An acceleration system for charged nuclear particles with mass number equal or greater than 1, comprising:

a rotating mechanical gantry structure;

at least one radiofrequency (RF) linear accelerator configured for producing a pulsed ion beam,

said accelerator comprising at least one linac section mounted on the rotating gantry structure, the accelerator configured for rotating around an axis to irradiate a target or patient from more than one direction with the produced pulsed ion beam, the produced pulsed ion beam configured for treating a patient tumor or malformation;

an ion source configured to produce an ion beam; and

a particle accelerator, configured as pre-accelerator to impart energy to particles within the ion beam, produced by the ion source, before injecting the ion beam into the linac section mounted on the rotating gantry structure,

wherein at least one of i) the ion source and ii) the pre-accelerator are mounted on the rotating gantry structure.

14. A system for ion acceleration according to claim 13, further comprising radio-frequency (RF) power generators mounted on the rotating gantry structure and directly connected to the at least one linac section.

15. An acceleration system for charged nuclear particles with mass number equal or greater than 1, comprising:

a rotating mechanical structure rotating around an axis; and

at least one radiofrequency (RF) linear accelerator configured to produce a pulse ion beam,

said at least one radiofrequency (RF) linear accelerator comprising at least one linac section mounted on the rotating mechanical structure, the accelerator configured to irradiate a target or patient from more than one direction with the produced pulsed ion beam, the produced ion beam configured for treating a patient tumor or malformation; and

a particle accelerator, configured as pre-accelerator and arranged to impart energy to particles within an ion beam before injecting the ion beam into the linac section, wherein the the pre-accelerator is one of i) a cyclotron, and ii) a Fixed Field Alternating Gradient(FFAG) accelerator.

16. A system for ion acceleration according to claim 15, wherein the pre-accelerator is a cyclotron.

17. A system for ion acceleration according to claim 15, wherein the pre-accelerator is a FFAG accelerator.