Treatment indications informed by a priori implant information

• US 8,409,132 B2
• Filed: 12/20/2007
• Issued: 04/02/2013
• Est. Priority Date: 12/18/2007
• Status: Expired due to Fees

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Ferren, Bran, Hyde, Roderick A., Ishikawa, Muriel Y., Leuthardt, Eric C., Rivet, Dennis J., Wood, Lowell L. Jr., Wood, Victoria Y. H.
• Primary Examiner(s): Mehta, Bhisma
• Application Number:
  US12/005,122
• Publication Number:
  US 20090157055A1
• Time in Patent Office: 1,930 Days
• Field of Search: 604/65, 604/66, 604/67, 604/266, 604/891.1
• US Class Current: 604/65
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61M 2005/1726 the body parameters being measured at, or proximate to, the infusion site
• CPC Class Codes: A61M 2039/2413 designed to reduce and or shut-off the flow when a certain maximum flow limit is exceeded
• CPC Class Codes: A61M 2039/242 designed to open when a predetermined pressure or flow rate has been reached, e.g. check valve actuated by fluid
• CPC Class Codes: A61M 2039/248 Ball-valve
• CPC Class Codes: A61M 2205/04 implanted
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 31/00 Devices for introducing or retaining media, e.g. remedies, in cavities of the body A61M25/00 takes precedence ; introducing or retaining ophthalmic products into the ocular cavities A61F9/0008
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 70/60 relating to pathologies

Abstract

Systems and methods are described for implementing or deploying therapeutic administration systems for obtaining a flow-change-indicative measurement and signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement.

Claims

1. A therapeutic administration system comprising:

one or more modules for obtaining a flow-change indicative measurement;

one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement;

a first dispenser operable for dispensing at least a lytic material;

a second dispenser operable for targeting an implant site; and

a wireless-communication device operable for communicating a selection of the first dispenser or the second dispenser.

2. The therapeutic administration system of claim 1 in which the one or more modules for obtaining a flow-change-indicative measurement comprise:

a module for programming an implantable device.

3. The therapeutic administration system of claim 1 in which the one or more modules for obtaining a flow-change-indicative measurement comprise:

a turbulence-indicative auditory valve as the flow-change-indicative measurement.

4. The therapeutic administration system of claim 1 in which the one or more modules for obtaining a flow-change-indicative measurement comprise:

a module for detecting one or more conditions optically.

5. The therapeutic administration system of claim 4 in which the one or more modules for obtaining a flow-change-indicative measurement comprise:

a turbulence-indicative auditory value as the flow-change-indicative measurement.

6. The therapeutic administration system of claim 1 in which the one or more modules for obtaining a flow-change-indicative measurement comprise:

a module for detecting one or more force-change-indicative values.

7. The therapeutic administration system of claim 6 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

a module for causing one or more dispensations in response to an apparent problem in the flow-change-indicative measurement.

8. The therapeutic administration system of claim 6, further comprising:

a thrombolytic-agent-containing dispenser responsive to the decision whether to administer the one or more clot-reducing agents.

9. The therapeutic administration system of claim 1 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

a module for deciding upon at least one of the one or more clot-reducing agents in response to obtaining an anomalous value as the flow-change-indicative measurement.

10. The therapeutic administration system of claim 1 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

a module for signaling at least an anticoagulant of the one or more clot-reducing agents in response to an apparent flow degradation.

11. The therapeutic administration system of claim 10 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

a module for one or more dispensations in response to an apparent problem in the flow-change-indicative measurement.

12. The therapeutic administration system of claim 1 in which one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

one or more instructions responsive to a flow-force-responsive element.

13. The therapeutic administration system of claim 1 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

one or more instructions responsive to an optical sensor.

14. The therapeutic administration system of claim 13, further comprising:

a thrombolytic-agent-containing dispenser responsive to the decision whether to administer the one or more clot-reducing agents.

15. The therapeutic administration system of claim 1 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

one or more instructions responsive to an auditory sensor.

16. The therapeutic administration system of claim 1 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

a module for causing one or more dispensations in response to an apparent problem in the flow-change-indicative measurement.

17. The therapeutic administration system of claim 1, further comprising:

a thrombolytic-agent-containing dispenser responsive to the decision whether to administer the one or more clot-reducing agents.

18. The therapeutic administration system of claim 1, further comprising:

an implant-site-targeting dispenser responsive to the decision whether to administer the one or more clot-reducing agents.

19. The therapeutic administration system of claim 1 in which the one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement comprise:

a module for signaling at least an anticoagulant of the one or more clot-reducing agents in response to an apparent flow degradation.

20. A therapeutic administration system comprising:

one or more modules for obtaining a flow-change-indicative measurement;

one or more modules for signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement;

a first dispenser operable for dispensing at least a clot-reducing agent;

a second dispenser operable for targeting an implant site; and

a wireless-communication device operable for communicating a selection of the first dispenser or the second dispenser.

21. A therapeutic administration method comprising:

obtaining a flow-change-indicative measurement;

signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement;

dispensing, from a first dispenser, at least a lytic material;

targeting, utilizing a second dispenser, an implant site and

communicating, using a wireless-communication device, a selection of the first dispenser or the second dispenser.