Microparticles
First Claim
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1. A method of forming particles, comprising:
- accelerating a first stream comprising a first liquid with a carrier stream that imposes frictional force on the first stream to accelerate the first stream;
applying a charging voltage to the first stream;
vibrating the first stream, to form particles; and
separating the particles into sub-particles with a device in-line with a flow of the particles, wherein the device comprises a blade or a nanowire.
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Accused Products
Abstract
A method of forming particles, comprises accelerating a first stream comprising a first liquid, applying a charging voltage of at most 1.5 kV to the first stream, and vibrating the first stream, to form particles.
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Citations
32 Claims
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1. A method of forming particles, comprising:
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accelerating a first stream comprising a first liquid with a carrier stream that imposes frictional force on the first stream to accelerate the first stream; applying a charging voltage to the first stream; vibrating the first stream, to form particles; and separating the particles into sub-particles with a device in-line with a flow of the particles, wherein the device comprises a blade or a nanowire. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 21, 22, 23, 24)
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18. A method of forming chitosan or alginate particles, comprising:
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accelerating a first stream comprising a solution of chitosan or alginate with a second stream that imposes frictional force on the first stream; applying a charging voltage to the first stream; vibrating the first stream, to form particles; separating the particles into sub-particles with a device in-line with a flow of the particles, wherein the device comprises a blade or a nanowire; and maintaining the sub-particles at a pressure of at least 0.1 mm Hg and of at most 760 mm Hg, while heating the sub-particles to a temperature within ±
50°
C. of the boiling point of water at the pressure;wherein the accelerating comprises contacting the first stream with the second stream, and the second stream comprises a hydrophobic liquid. - View Dependent Claims (19, 25, 26, 27, 28)
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20. A method of forming gelatin particles, comprising:
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accelerating a first stream with a second stream, applying a charging voltage to the first stream; vibrating the first stream, to form particles; separating the particles into sub-particles with a device in-line with a flow of the particles, wherein the device comprises a blade or a nanowire, and wherein the accelerating comprises contacting the first stream with the second stream. - View Dependent Claims (29, 30, 31, 32)
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Specification