Rotational thrombectomy wire with blocking device

• US 8,414,543 B2
• Filed: 08/23/2010
• Issued: 04/09/2013
• Est. Priority Date: 10/22/1999
• Status: Expired due to Term

• Current Assignee: Argon Medical Devices
• Original Assignee: REX Medical LP
• Inventors: McGuckin, James F. Jr., Leedle, John D., Bressler, James Erich, Hinchliffe, Peter W. J.
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US12/861,110
• Publication Number:
  US 20110040314A1
• Time in Patent Office: 960 Days
• Field of Search: 604/96.01, 604/101.01, 604 9701- 9703, 604 9901- 9904, 60410102-10105, 60410201-10203, 604/103.07, 604/104, 604/915, 604/916, 604/22, 604/27, 604/35, 604/266, 604/267
• US Class Current: 604/247
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22032 having inflatable gripping elements balloon catheters A61M25/10
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: B82Y 10/00 Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic

Abstract

A thrombectomy apparatus for breaking up thrombus or other obstructive material in a lumen of a vascular graft or vessel. The apparatus includes a wire having a first configuration and a second deployed configuration, the wire having a straighter configuration in the first configuration. The wire is operatively connected to a motor for rotation of the wire to contact and break up the thrombus or other obstructive material. A blocking device at a distal portion of the apparatus is movable between a collapsed configuration and an expanded configuration, and is configured in the expanded configuration to block thrombus dislodged by rotation of the wire.

Claims

1. A thrombectomy apparatus for breaking up thrombus or other obstructive material in a lumen of a vascular graft or vessel, the apparatus comprising a thrombectomy wire having a first configuration and a second deployed configuration when exposed from a sheath, the wire having a straighter configuration in the first configuration, the wire being operatively connected to a motor for rotation of the wire to contact and break up the thrombus or other obstructive material, and a blocking device at a distal portion of the apparatus and connected to the thrombectomy wire such that the blocking device is advanced together with the thrombectomy wire into the lumen of the graft or vessel, the blocking device movable between a collapsed configuration and an expanded configuration, the blocking device in the expanded configuration configured to block thrombus dislodged by rotation of the wire.

2. The thrombectomy apparatus of claim 1, wherein the wire is sinuous in configuration and assumes its sinuous configuration when in the deployed configuration.

3. The thrombectomy apparatus of claim 1, wherein the wire is composed of an inner core and an outer coil.

4. The thrombectomy apparatus of claim 3, wherein the inner core is composed of a plurality of wires twisted together.

5. The thrombectomy apparatus of claim 1, wherein the wire spins independent of the blocking device such that the blocking device remains substantially stationary as the wire rotates.

6. The thrombectomy apparatus of claim 1, wherein the blocking device includes a tubular portion connected to a distal end of the wire, the wire rotatable independent of the tubular portion.

7. The thrombectomy apparatus of claim 6, further comprising an inflatable balloon, the balloon spaced proximally of a distal tip of the wire.

8. The thrombectomy apparatus of claim 1, wherein the wire terminates in a J-tip.

9. The thrombectomy apparatus of claim 1, further comprising a flexible sheath.

10. The thrombectomy apparatus of claim 9, further comprising first and second balloons, and the flexible sheath has first and second lumens, the first lumen communicating with the first balloon and the second lumen communicating with the second balloon.

11. The thrombectomy apparatus of claim 10, wherein the first balloon is an angioplasty balloon and the second balloon is configured for engaging and pulling an arterial plug, wherein the first balloon is proximal of the second balloon.

12. The thrombectomy apparatus of claim 1, further comprising a housing, the wire extending from the housing, the housing containing a battery and the motor for rotating the wire.

13. The thrombectomy apparatus of claim 1, wherein the blocking device includes a plurality of wires and a porous material covering at least a portion of the wires.

14. The thrombectomy apparatus of claim 13, wherein the material covers a distal portion of the wires.

15. The thrombectomy apparatus of claim 1, wherein the blocking device includes an expandable material and a plurality of wires expandable to expand the material.

16. The thrombectomy apparatus of claim 1, wherein in the second configuration the wire has a first arcuate region extending in a first direction and a second arcuate region spaced longitudinally from the first arcuate region and extending in a second direction, the first and second arcuate regions configured to break up thrombotic material as the wire spins.

17. A thrombectomy apparatus for breaking up thrombus comprising a rotatable thrombectomy wire, the wire having a non-linear configuration, a blocking device connected to a distal portion of the wire distally of the non-linear portion of the wire, the blocking device advanceable together with the thrombectomy wire and expanding radially with respect to the wire, and a motor for rotating the wire to break up thrombotic material as the wire rotates about its axis.

18. The apparatus of claim 17, wherein the wire is rotatable independent of the blocking device.

19. The apparatus of claim 18, wherein the wire includes a multifilar outer wire surrounding at least a portion of an inner core, the multifilar outer wire including at least first and second metal wires wound side by side and having a sinuous shaped portion at a distal region and a polymeric material surrounding at least a distal portion of the multifilar wire.

20. A method for breaking up thrombotic material from a lumen of a vascular graft or vessel comprising;

inserting a sheath;

inserting a thrombectomy apparatus having a rotatable thrombectomy wire and a blocking device connected to the thrombectomy wire;

exposing the rotatable thrombectomy wire of the thrombectomy apparatus from the sheath to enable the blocking device to move from a collapsed position to an expanded position;

rotating the wire to break up thrombotic material; and

blocking at least some of the thrombotic material with the blocking device positioned at a distal portion of the thrombectomy wire; and

withdrawing the thrombectomy wire to withdraw the blocking device.

21. The method of claim 20, wherein the step of rotating the wire includes the step of rotating the wire while the blocking device does not rotate.

22. The method of claim 21, wherein the blocking device is movable to the collapsed position for withdrawal.