Removable lung reduction devices, systems, and methods

• US 8,414,655 B2
• Filed: 07/01/2010
• Issued: 04/09/2013
• Est. Priority Date: 09/11/2001
• Status: Expired due to Term

• Current Assignee: Gyrus ACMI, Inc. (Olympus Corporation)
• Original Assignee: Spiration, Inc. (Olympus Corporation)
• Inventors: Alferness, Clifton A., Gonzalez, Hugo X., Dillard, David H.
• Primary Examiner(s): Philogene, Pedro
• Application Number:
  US12/828,629
• Publication Number:
  US 20110054632A1
• Time in Patent Office: 1,013 Days
• Field of Search: 606/108, 606/198, 606/191, 606/106, 606/200, 128/200.26, 128/200.24, 128/207.15, 128/207.14, 128/207.16, 623/23.65
• US Class Current: 623/23.65
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61F 2002/043 Bronchi
• CPC Class Codes: A61M 16/0404 with means for selective or partial lung respiration

Abstract

An air passageway obstruction device includes a frame structure and a flexible membrane overlying the frame structure. The frame structure is collapsible upon advancement of the device into the air passageway, expandable into a rigid structure upon deploying in the air passageway and recollapsible upon removal from the air passageway. The flexible membrane obstructs inhaled air flow into a lung portion communicating with the air passageway. The device may be removed after deployment in an air passageway by recollapsing the device and pulling the device proximally through a catheter.

Claims

1. A method of moving a device in an air passageway, wherein the device comprises a flexible frame with at least one frame support, the frame support further comprising at least one fixation projection configured to extend inwardly into the air passageway while deployed, wherein the at least one fixation projection is configured to release from the air passageway when pulled in a proximal direction, the method of moving the device comprising:

advancing a catheter through a trachea and into the air passageway, the catheter having at least one internal lumen;

advancing a retractor through the internal lumen of the catheter to the device;

grasping a portion of the device with the retractor;

collapsing the device to free the device from deployment in the air passageway; and

advancing the catheter over at least a portion of the retractor and a proximal end of the device; and

withdrawing the catheter from the air passageway and trachea.

2. The method of moving the device of claim 1, wherein the device further comprises a proximal portion located in an axially-central location, and wherein grasping comprises grasping the proximal section of the device with the retractor.

3. The method of moving the device of claim 1, wherein the step of collapsing the device releases the at least one fixation projection from the air passageway.

4. The method of moving the device of claim 1, wherein the device is collapsible so as to fit within the internal lumen of the catheter.

5. The method of moving the device of claim 1, wherein the device further comprises a membrane configured to contact an air passageway wall.

6. The method of moving the device of claim 1, further comprising pulling the device and retractor proximally into the internal lumen of the catheter after collapsing the device.

7. The method of moving the device of claim 1, further comprising the step of removing the device from the air passageway.

8. A kit for moving a device, the device being collapsible and dimensioned for insertion into an air passageway communicating with a portion of a lung to be treated, the device being movable from a collapsed position to a deployed position, the device further comprising at least one anchor configured to engage the air passageway when the device is in a deployed position, and wherein the at least one anchor is configured to release from the air passageway when pulled in a proximal direction, and wherein the kit comprises:

a catheter having an internal lumen and being dimensioned to fit within the air passageway; and

a retractor configured to fit within the internal lumen of the catheter and comprising at a distal end a member for engaging the device to remove the device from the air passageway.

9. The kit of claim 8, wherein the retractor is configured to pull the device proximally into the internal lumen of the catheter.

10. The kit of claim 9, wherein the catheter is configured to collapse the device as the device is pulled into the internal lumen of the catheter.

11. The kit of claim 8, wherein the device comprises at least one anchor is disposed at a distal end.

12. The kit of claim 8, wherein the device forms a one-way valve.

13. The kit of claim 8, wherein the device comprises a collapsible frame and a flexible membrane overlying the collapsible frame.

14. The kit of claim 13, wherein the device has an open proximal end and a closed distal end.

15. The kit of claim 14, wherein the flexible membrane is configured to preclude air from flowing into the lung portion by at least partially inflating in response to air flowing in a distal direction, and wherein the flexible membrane is configured to permit air to flow out of the lung portion by at least partially deflating in response to air flowing in a proximal direction.

16. The kit of claim 8, wherein the retractor is configured to engage a centrally-located proximal rod on the device.

17. The kit of claim 8, wherein the retractor is a forceps.

18. The kit of claim 8, wherein the catheter is dimensioned to fit within a bronchoscope.