Electromagnetic treatment apparatus and method for angiogenesis modulation of living tissues and cells
First Claim
1. A method for electromagnetic treatment of living tissues and cells by enhancing angiogenesis and neovascularization comprising the steps of:
- applying a portable electromagnetic treatment device adjacent to a target tissue site;
generating an electromagnetic signal from at least one waveform; and
coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device; and
inducing an electromagnetic field at the target tissue site from the at least one waveform, wherein said at least one waveform is configured to be coupled to an angiogenesis and neovascularization target pathway structure at the target tissue site by modulating binding of calcium to Calmodulin, wherein the waveform induces a power that is greater than the thermal noise power of calcium binding to Calmodulin so that the at least one waveform is configured to be detectable in said angiogenesis and neovascularization target pathway structure above background activity in said angiogenesis and neovascularization target pathway structure.
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Abstract
An apparatus and method for electromagnetic treatment of living tissues and cells comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a angiogenesis and neovascularization target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said angiogenesis and neovascularization target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device.
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Citations
24 Claims
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1. A method for electromagnetic treatment of living tissues and cells by enhancing angiogenesis and neovascularization comprising the steps of:
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applying a portable electromagnetic treatment device adjacent to a target tissue site; generating an electromagnetic signal from at least one waveform; and coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device; and inducing an electromagnetic field at the target tissue site from the at least one waveform, wherein said at least one waveform is configured to be coupled to an angiogenesis and neovascularization target pathway structure at the target tissue site by modulating binding of calcium to Calmodulin, wherein the waveform induces a power that is greater than the thermal noise power of calcium binding to Calmodulin so that the at least one waveform is configured to be detectable in said angiogenesis and neovascularization target pathway structure above background activity in said angiogenesis and neovascularization target pathway structure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A method for electromagnetic treatment of living tissues and cells by enhancing angiogenesis and neovascularization comprising the steps of:
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applying a portable electromagnetic treatment device adjacent to a target tissue site; generating an electromagnetic signal from at least one waveform; and coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device; and inducing an electromagnetic field at the target tissue site from the at least one waveform, wherein said at least one waveform is configured to be coupled to an angiogenesis and neovascularization target pathway structure at the target tissue site, wherein the waveform is further configured to have a time constant that matches the bandpass of calcium binding to Calmodulin according to an electrically equivalent model of calcium binding to Calmodulin, and wherein the waveform is configured to induce a power at the target tissue that is greater than the thermal noise power of calcium binding to Calmodulin.
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Specification