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Methods, materials, and apparatus for treating bone and other tissue

  • US 8,415,407 B2
  • Filed: 02/22/2006
  • Issued: 04/09/2013
  • Est. Priority Date: 03/21/2004
  • Status: Active Grant
First Claim
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1. A bone cement comprising:

  • a first liquid component containing MMA (methyl methacrylate) monomers; and

    a second powder component containing pre-polymerized PMMA (polymethyl methacrylate) beads having an average molecular weight and further containing a population of pre-polymerized PMMA beads having a high molecular weight,wherein, the average molecular weight, the high molecular weight, and the percentage of beads having the high molecular weight are selected so that contacting the first component and the second component produces a mixture which achieves a high viscosity during an initial period, has a stable viscosity during a working time, and solidifies after the working time;

    wherein the mixture attains the high viscosity of greater than 900 Pascal seconds within the initial period of about 180 seconds following initiation of mixing of the first liquid component and the second powder component,wherein the working time is for at least 5 minutes and the working time follows the initial period;

    wherein the viscosity of the mixture is between 900 Pascal seconds and 2000 Pascal seconds during the working time;

    wherein the viscosity of the mixture changes by less than 200 Pascal seconds during a window of at least 2 minutes after mixing; and

    wherein the mixture is suitable for in-vivo use.

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