Leak-compensated pressure regulated volume control ventilation
First Claim
1. A method of compensating for leakage in a ventilation system during delivery of pressure regulated volume control ventilation to a patient, the method performed by the ventilation system, the method comprising:
- monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system;
modeling, by the ventilation system, leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system;
estimating a leak-compensated delivered lung volume for at least one breath based on the one or more measurements, the first leakage component and the second leakage component;
using the leak-compensated delivered lung volume and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance; and
calculating a target pressure to be delivered to the patient for a subsequent breath based on a desired lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance.
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Abstract
This disclosure describes systems and methods for compensating for leakage when during delivery of gas to a patient from a medical ventilator in a pressure regulated volume control (PRVC) ventilation mode. The technology described herein includes systems and methods that compensate the delivery of PRVC ventilation for leakage in the patient circuit by using leak-compensated lung flows as well as respiratory mechanics (lung compliance and lung resistance) estimated in a manner that compensates for elastic and inelastic leaks from the ventilation system.
633 Citations
10 Claims
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1. A method of compensating for leakage in a ventilation system during delivery of pressure regulated volume control ventilation to a patient, the method performed by the ventilation system, the method comprising:
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monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system; modeling, by the ventilation system, leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system; estimating a leak-compensated delivered lung volume for at least one breath based on the one or more measurements, the first leakage component and the second leakage component; using the leak-compensated delivered lung volume and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance; and calculating a target pressure to be delivered to the patient for a subsequent breath based on a desired lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method of compensating for leakage in a ventilation tubing system during delivery of gas from a medical ventilator to a patient, the method performed by the medical ventilator, the method comprising:
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measuring leakage from the ventilation tubing system during a first breath; calculating, by the medical ventilator., a leak-compensated delivered lung volume for the first breath based on the leakage; estimating a lung compliance of the patient based on the leak-compensated delivered lung volume and pressure measurements taken during the first breath; and delivering ventilation to the patient in a second breath at a pressure determined based on a desired delivered lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance. - View Dependent Claims (8, 9, 10)
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Specification