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Leak-compensated pressure regulated volume control ventilation

  • US 8,418,691 B2
  • Filed: 03/20/2009
  • Issued: 04/16/2013
  • Est. Priority Date: 03/20/2009
  • Status: Active Grant
First Claim
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1. A method of compensating for leakage in a ventilation system during delivery of pressure regulated volume control ventilation to a patient, the method performed by the ventilation system, the method comprising:

  • monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system;

    modeling, by the ventilation system, leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system;

    estimating a leak-compensated delivered lung volume for at least one breath based on the one or more measurements, the first leakage component and the second leakage component;

    using the leak-compensated delivered lung volume and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance; and

    calculating a target pressure to be delivered to the patient for a subsequent breath based on a desired lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance.

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