Systems, methods and apparatus for respiratory support of a patient

• US 8,418,694 B2
• Filed: 04/30/2010
• Issued: 04/16/2013
• Est. Priority Date: 08/11/2003
• Status: Active Grant

• Current Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Original Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Inventors: Freitag, Lutz, Kapust, Gregory
• Primary Examiner(s): DOUGLAS, STEVEN O
• Application Number:
  US12/771,651
• Publication Number:
  US 20100269834A1
• Time in Patent Office: 1,082 Days
• Field of Search: 128/200.26, 128/207.14, 128/207.15, 128/207.16, 128/207.24, 128/204.18, 128/204.23, 623/9, 604/99.01, 604/102.01, 604/103.01
• US Class Current: 128/207.14
• CPC Class Codes: A61M 16/00 Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes stimulating the respiratory movement by mechanical, pneumatic or electrical means, iron lungs combined with gas breathing means A61H31/00
• CPC Class Codes: A61M 16/0006 with means for creating vibrations in patients' airways
• CPC Class Codes: A61M 16/0063 Compressors
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/0465 Tracheostomy tubes; Devices for performing a tracheostomy; Accessories therefor, e.g. masks, filters
• CPC Class Codes: A61M 16/0468 with valves at the proximal end limiting exhalation, e.g. during speaking or coughing air passages from trachea to oesophagus or to pharynx, artificial epiglottis A61F2/203
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0413 with detectors of CO2 in exhaled gases

Abstract

Spontaneous respiration is detected by sensors. An additional amount of oxygen is administered to the lungs via a jet gas current at the end of an inhalation procedure. Breathing volume, absorption of oxygen during inhalation, and clearance of carbon dioxide during exhalation are improved. If required, the exhalation procedure of the patient can be arrested or slowed by a countercurrent to avoid a collapse of the respiration paths. An apparatus including an oxygen pump can be connected to an oxygen source and includes a tracheal prosthesis that can be connected via a catheter. The respiration detections sensors are connected to a control unit for activating the oxygen pump. The tracheal prosthesis includes a tubular support body with a connection for the catheter, and the sensors are associated with the support body. The tracheal prosthesis and jet catheter are dimensioned so the patient can freely breathe and speak without restriction.

Claims

1. A method or supporting the respiration of a patient comprising the steps of:

detecting the spontaneous respiration of the patient with sensors,

identifying an end of an inhalation process of the spontaneous respiration.

administering an additional amount of oxygen-bearing gas to the lungs through an oxygen-bearing gas delivery device into a respiratory system of the patient, and

wherein the oxygen-bearing gas delivery device and the additional amount of oxygen-bearing gas allows the patient to speak unhindered.

2. The method of claim 1, wherein the amount of oxygen-bearing gas is sufficient to treat sleep apnea, COPD, emphysema, pulmonary fibrosis, sarcoidosis, pleural adhesions, chest-wall diseases, neuromuscular diseases, or phrenic nerve paralysis.

3. The method of claim 1, wherein the amount of oxygen-bearing gas is sufficient to prevent the patient'"'"'s airway from collapsing.

4. The method of claim 1, wherein the sensors include thennistors, respihands, respitrace, or transthoraeieal electrical impedance measuring devices.

5. The method of claim 1, wherein the sensors are disposed at different locations.

6. The method of claim 5, further comprising dampening a signal response of a sensor relative to a signal response of an additional sensor, and comparing the signal response of the sensor and the signal response of the additional sensor for correcting signal drift transient signals and artifacts.

7. The method of claim 1, wherein inspiration and exhalation are determined with a bridge circuit and a differentiator,

9. The method of claim 1, wherein the oxygen-bearing gas delivery device comprises a tracheal prosthesis.

10. The method of claim 9, further comprising the step of securing the tracheal prosthesis in a trachea.

11. The method of claim 9, wherein the tracheal prosthesis has a circular or semicircular cross-section.

12. The method of claim 9, wherein the tracheal prosthesis further comprises a coupling adapted to receive a catheter.

13. The method of claim 1, wherein the oxygen-bearing gas is administered by jet flow.

14. The method of claim 13, wherein the oxygen-bearing gas is administered at a speed of approximately 100 m/s to 300 m/s.

15. The method of claim 14, wherein the oxygen-bearing gas is administered at a speed of approximately 200 m/s to 300 m/s.

16. The method of claim 15, wherein the oxygen-bearing gas is administered at a speed of approximately 250 m/s to 300 m/s.

17. The method of claim 1, wherein the oxygen-bearing gas delivery device comprises a catheter.

18. The method of claim 17, wherein the catheter comprises an outer lumen and an inner lumen.

19. The method of claim 17, wherein a flow of the oxygen-bearing gas is directed substantially down the center of a trachea.

20. The method of claim 1, wherein the oxygen-bearing gas is administered only on inspiration.

21. The method of claim 1, wherein the oxygen-bearing gas is administered only on expiration.

22. The method of claim 1, wherein the oxygen-bearing gas is administered during both inhalation and exhalation.

23. The method of claim 22, wherein the additional amount of oxygen-bearing gas causes flow braking turbulence or the addition of venture flow.

24. The method of claim 1, wherein information from the sensors can be communicated to a healthcare provider or hospital for monitoring.

33. The method of claim 1, wherein the oxygen-bearing gas delivery device comprises a tracheal prosthesis.

34. The method of claim 33, further comprising the step of securing the tracheal prosthesis in a trachea.

35. The Method of claim 33, wherein the tracheal prosthesis has a circular or semicircular cross-section.

36. method of claim 33, wherein the tracheal prosthesis further comprises a coupling adapted to receive a catheter.

8. The method of chum 7, wherein inspiration is determined at a minimum absolute temperature and a differentiated signal of zero.

25. A method for supporting the respiration of a patient Comprising the steps:

detecting the spontaneous respiration of the patient with sensors,

administering an additional amount of oxygen-bearing gas through an oxygen-bearing gas delivery device into is respiratory system of the patient, wherein the oxygen-bearing gas increases the depth of the patent'"'"'s ventilation and/or reduces the patient'"'"'s work of breathing, and

wherein the oxygen-bearing gas delivery device does ma inhibit the patient from breathing freely from ambient air.

26. The method of claim 25, wherin the amount of oxygen-bearing gas is sufficient to treat sleep apnea, COPD,emphysema, pulmonary fibrosis, sarcoidosis, plaurai adhesions, chest-wall diseases, neuromusco diseases, or phrenic nerve paralysis.

27. The method of claim 25, wherein the amount of oxygen-bearing gas is sufficient to prevent the patients airway from collapsing.

28. The method of claim 25, wherein the sensors include thermistors, respibands, respitrace, or transthoracical electrical impedance measuring devices.

29. The method of claim 25, wherein the sensors are disposed at different locations.

30. The method of claim 29, further comprising dampening a signal response of a sensor relative to a signal response of an additional sensor, and comparing the signal response of the sensor and the signal response of the additional sensor for correcting signal drift, transient signals and artifacts.

31. The method of claim 25, wherein the oxygen-bearing gas selectively supplements the patient'"'"'s inspiration of ambient air.

32. The method of claim 31, wherein the increased depth of the patient'"'"'s ventilation and/or reduction in the patient'"'"'s work of breathing is facilitated by the oxygen-bearing gas delivery device.

37. The method of claim 25, wherein the oxygen-bearing gas is administered by jet flow.

38. The method of claim 37, wherein the oxygen-bearing gas is administered at to speed of approximately 100 m/s to 300 m/s.

39. The method of claim 25, wherein the oxygen-bearing gas delivery device comprises a catheter.

40. The method of claim 39, wherein the catheter comprises an outer lumen and an inner lumen.

41. The method of claim 39, wherein a flow of the oxygen-bearing gas is directed substantially down the center of a trachea.

42. The method of claim 25, wherein the oxygen-bearing, gas is administered only on inspiration,

43. The method of claim 25 wherein the oxygen-bearing, gas is administered only on expiration.

44. The method of claim 25, wherein the oxygen-bearing gas is administered during both inhalation and exhalation.

45. The method of claim 44, wherein the additional amount of Oxygen-bearing gas causes flow braking turbulence or the addition of venturi flow.

46. The method of claim 25, wherein information from the sensors can be communicated to a healthcare provider or hospital for monitoring.

47. A method for supporting the respiration of a patient comprising the steps of:

detecting the spontaneous respiration of the patient with sensors,

administering an additional amount of oxygen-bearing as through an oxygen-bearing gas delivery device into a respiratory system of the patient, wherein the oxygen-bearing gas increases the depth of the patient'"'"'s ventilation and/or reduces the patient'"'"'s work of breathing, and

wherein the oxygen-bearing gas delivery device and the additional amount of oxygen-bearing gas allows the patient to speak unhindered.

48. The method of claim 47, further comprising dampening a signs response of a sensor relative to a signal response of an additional sensor, and comparing the signal response of the sensor and the signal response of the additional sensor for correcting signal drift, transient signals and artifacts.

49. The method of claim 47, wherein the oxygen-bearing gas is administered only on inspiration.

50. The method of claim 47, wherein the oxygen-bearing gas is administered only on expiration.

51. The method of claim 47, wherein the oxygen-bearing gas is administered during both inhalation and exhalation.

52. A method for supporting the respiration of a patient Comprising:

operatively interfacing an oxygen-bearing gas delivery device to the respiratory system of the patient,

fluidly connecting to the oxygen-bearing gas delivery device to an oxygen-bearing gas source,

operatively interfacing at least one sensor to the patient,

operatively interfacing a control unit to the sensor and the oxygen-bearing gas source, and

selectively activating the oxygen-bearing gas source based on a signal provided to the control unit connected by the sensor,

wherein an oxygen-hearing gas provided to the patient by the oxygen-bearing gas source increases the depth of the padent'"'"'s ventilation and/or reduces the patient'"'"'s work of breathing, and wherein the oxygen-bearing gas delivery device does not inhibit the patient from breathing freely from ambient air.

53. The method of claim 52, further comprising the step of detecting the spontaneous respiration of the patient through the use of the sensor.

54. In The method of claim 52, wherein the step of operatively interfacing at least one sensor to the patient comprises operatively interfacing at least first and second sensors to the patient.

55. The method of claim 54, wherein the step of operatively interfacing at least first and second sensors to the patient sensors further comprises disposing the first and second sensors at different locations.

56. The method of claim 55, further comprising the step of dampening a signal response of the first sensor to a signal response of the second sensor, and comparing the signal response of the first sensor to the signal response of the second sensor for correcting signal drift, transient signals and artifacts.

57. The method of claim 55, further comprising step of implanting at least one of the first and second sensors into the patient'"'"'s body.

58. The method of claim 52, wherein the oxygen-bearing gas selectively supplements the patient'"'"'s inspiration of ambient air.

59. The method of claim 58, wherein the increased depth of the patients ventilation and/or reduction in the patient'"'"'s work of breathing is facilitated by the oxygen-bearing gas delivery device.

60. A method for supporting the respiration of a patient comprising:

operatively interfacing an oxygen-bearing gas delivery device, to the respiratory system of the patient,

fluidly connecting to the oxygen-bearing gas delivery device to an oxygen-bearing gas source,

operatively, interfacing at least one sensor to the patient,

operatively interfacing a control unit to the sensor and the oxygen-bearing gas source, and

selectively activating the oxygen-bearing gas source based on a signal provided to the control unit connected by the sensor,

wherein an oxygen-bearing gas provided to the patient by the oxygen-bearing gas source increases the depth of the patient'"'"'s ventilation and/or reduces the patient'"'"'s work of breathing, and wherein the oxygen-bearing gas delivery device allows the patient to speak unhindered.

61. The method of claim 60, wherein the step of operatively interfacing at least one sensor to the patient comprises operatively interfacing at least first and second sensors to the patient.

62. The method of claim 61, wherein the step of operatively interfacing at least first and second sensors to the patient sensors further comprises disposing the first and second sensors at different locations.

63. The method of claim 61, further comprising the step of dampening a signal response of the first sensor relative to a signal response of the second sensor, and comparing the signal response of the first sensor to the signal response of the second sensor for correcting signal drift, transient signals and artifacts.

64. The method of claim 61, further comprising the step of implanting at least one of the first and second sensors into the patients body.