Electrical stimulation to alleviate chronic pelvic pain

• US 8,423,146 B2
• Filed: 08/23/2010
• Issued: 04/16/2013
• Est. Priority Date: 01/31/2006
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Giftakis, Jonathon E., Gerber, Martin T.
• Primary Examiner(s): Gedeon, Brian T
• Application Number:
  US12/861,165
• Publication Number:
  US 20100318157A1
• Time in Patent Office: 967 Days
• Field of Search: 600/347, 607/39, 607/45, 607/46
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36071 Pain

Abstract

The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.

Claims

1. A system comprising:

an implantable stimulation device configured to generate electrical stimulation selected to alleviate pelvic pain of a patient; and

a processor configured to control the implantable stimulation device to apply the electrical stimulation to a genital nerve branch of a genitofemoral nerve of the patient at a point after the genitofemoral nerve has branched to form the genital nerve branch and a femoral nerve branch.

2. The system of claim 1,

wherein the processor is configured to control the implantable stimulation device to apply the electrical stimulation to the genital nerve branch via a spermatic cord of the patient.

3. The system of claim 1,

wherein the processor is configured to control the implantable stimulation device to apply the electrical stimulation to the genital nerve branch at a point on a side of an inguinal canal of the patient opposite a spermatic cord of the patient.

4. The system of claim 1,

wherein the processor is configured to control the implantable stimulation device to apply the electrical stimulation to the genital nerve branch at a point on a side of an inguinal canal of the patient adjacent a spermatic cord of the patient.

5. The system of claim 1,

wherein the genital nerve branch of the genitofemoral nerve comprises a first genital nerve branch,

wherein the electrical stimulation comprises a first electrical stimulation,

wherein the implantable stimulation device is further configured to generate a second electrical stimulation, and

wherein the processor is further configured to control the implantable stimulation device to apply the second electrical stimulation to a second genital nerve branch of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve has branched to form the second genital nerve branch and a second femoral nerve branch.

6. The system of claim 5,

wherein the processor is configured to control the implantable stimulation device to apply the first electrical stimulation to the first genital nerve branch via a first spermatic cord of the patient, and

wherein the processor is configured to control the implantable stimulation device to apply the second electrical stimulation to the second genital nerve branch via a second spermatic cord of the patient.

7. The system of claim 5,

wherein the processor is configured to control the implantable stimulation device to apply the first electrical stimulation to the first genital nerve branch at a point on a side of a first inguinal canal that is opposite a first spermatic cord of the patient, and

wherein the processor is configured to control the implantable stimulation device to apply the second electrical stimulation to the second genital nerve branch at a point on a side of a second inguinal canal that is opposite a second spermatic cord of the patient.

8. The system of claim 5,

wherein the processor is configured to control the implantable stimulation device to apply the first electrical stimulation to the first genital nerve branch at a point on a side of a first inguinal canal that is adjacent to a first spermatic cord of the patient, and

wherein the processor is configured to control the implantable stimulation device to apply the second electrical stimulation to the second genital nerve branch at a point on a side of a second inguinal canal that is adjacent to a second spermatic cord of the patient.

9. The system of claim 1, wherein the implantable stimulation device is configured to generate the electrical stimulation that is selected to alleviate pelvic pain comprising at least one of chronic testicular pain, post vasectomy pain, genitofemoral neuralgia, vulvodynia, and interstitial cystitis.

10. The system of claim 1, further comprising an electrode coupled to the implantable stimulation device,

wherein the electrode is configured to at least partially engage a portion of a spermatic cord of the patient.

11. The system of claim 10, wherein the electrode includes at least one of a cuff electrode, a ring electrode, a planar electrode and an electrode on a leadless stimulator.

12. The system of claim 10, wherein the electrode includes a cuff electrode including a cuff-like fixation structure and one or more electrodes.

13. The system of claim 12, further comprising an implantable medical lead coupled to the implantable stimulation device, wherein the cuff electrode is mounted on the implantable medical lead.

14. The system of claim 12,

wherein the implantable stimulation device includes a leadless stimulator, and

wherein the cuff electrode is mounted on the leadless stimulator.

15. The system of claim 14,

wherein the fixation structure is flexible and at least partially conformable to the spermatic cord.

16. The system of claim 1, wherein the implantable stimulation device includes a leadless stimulator configured to be at least partially implanted within a facia of a spermatic cord of the patient.

17. The system of claim 1,

wherein the genital nerve branch of the genitofemoral nerve comprises a first genital nerve branch,

wherein the electrical stimulation comprises a first electrical stimulation,

wherein the implantable stimulation device is further configured to generate a second electrical stimulation,

wherein the processor is further configured to control the implantable stimulation device to apply the second electrical stimulation to a second genital nerve branch of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve has branched to form the second genital nerve branch and a second femoral nerve branch, and

wherein the processor is further configured to control the implantable stimulation device to apply the first electrical stimulation to the first genital nerve branch at a point prior to the first genital nerve branch entering a first inguinal canal of the patient, and to apply the second electrical stimulation to the second genital nerve branch at a point after the second genital nerve branch exits a second inguinal canal of the patient.

18. A system comprising:

means for generating first and second electrical stimulation, each of the first and second electrical stimulation selected to alleviate pelvic pain of a patient;

means for applying the first electrical stimulation to at least a portion of a first genitofemoral nerve of a patient at a point prior to the first genitofemoral nerve entering a first inguinal canal of the patient; and

means for applying the second electrical stimulation to at least a portion of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve exits a second inguinal canal of the patient.

19. The system of claim 18,

wherein the means for applying the first electrical stimulation comprises means for applying the first electrical stimulation to at least the portion of the first genitofemoral nerve comprises means for applying the electrical stimulation to a genital nerve branch of the first genitofemoral nerve on a side of the first inguinal canal of the patient that is opposite a first spermatic cord of the patient.

20. The system of claim 18,

wherein the means for applying the second electrical stimulation comprises means for applying the second electrical stimulation to at least the portion of the second genitofemoral nerve comprises applying the electrical stimulation to a genital nerve branch of the second genitofemoral nerve on a side of the second inguinal canal of the patient that is adjacent a second spermatic cord of the patient.

21. The system of claim 18,

further comprising an electrode coupled to the means for applying first electrical stimulation, the electrode being configured to at least partially engage a portion of a spermatic cord of the patient.

22. The system of claim 21, wherein the electrode comprises a cuff electrode comprising a cuff-like fixation structure and one or more electrodes, and wherein the cuff-like fixation structure is flexible and at least partially conformable to the spermatic cord.

23. A computer-readable storage medium comprising instructions that, when executed, cause a programmable processor to:

control an implantable stimulation device to apply electrical stimulation to a genital nerve branch of a genitofemoral nerve of a patient at a point after the genitofemoral nerve has branched to form the genital nerve branch and a femoral nerve branch, wherein the electrical stimulation is selected to alleviate pelvic pain of the patient.

24. The computer-readable storage medium of claim 23, wherein the genital nerve branch of the genitofemoral nerve comprises a first genital nerve branch and the electrical stimulation comprises a first electrical stimulation, and wherein the instructions, when executed, further cause the programmable processor to control the implantable stimulation device to apply second electrical stimulation to a second genital branch of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve has branched to form the second genital nerve branch and a second femoral nerve branch.

25. A system comprising:

means for generating electrical stimulation selected to alleviate pelvic pain of a patient; and

means for applying the electrical stimulation to a genital nerve branch of a genitofemoral nerve of the patient at a point after the genitofemoral nerve has branched to form the genital nerve branch and a femoral nerve branch.

26. The system of claim 25, wherein the means for applying the electrical stimulation comprises means for applying the electrical stimulation to the genital nerve branch via a spermatic cord of the patient.

27. The system of claim 25, wherein the means for applying the electrical stimulation comprises means for applying the electrical stimulation to the genital nerve branch at a point on a side of an inguinal canal of the patient opposite a spermatic cord of the patient.

28. The system of claim 25, wherein the means for applying the electrical stimulation comprises means for applying the electrical stimulation to the genital nerve branch at a point on a side of an inguinal canal of the patient adjacent a spermatic cord of the patient.

29. The system of claim 25, wherein the genital nerve branch of the genitofemoral nerve comprises a first genital nerve branch and the electrical stimulation comprises a first electrical stimulation, the system further comprising:

means for applying a second electrical stimulation to a second genital nerve branch of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve has branched to form the second genital nerve branch and a second femoral nerve branch.

30. A system comprising:

an implantable stimulation device configured to generate first and second electrical stimulation, each of the first and second electrical stimulation selected to alleviate pelvic pain of a patient; and

a processor configured to;

control the implantable stimulation device to apply the first electrical stimulation to at least a portion a first genitofemoral nerve of a patient at a point prior to the first genitofemoral nerve entering a first inguinal canal of the patient, and

control the implantable stimulation device to apply the second electrical stimulation to at least a portion of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve exits a second inguinal canal of the patient.

31. A computer-readable storage medium comprising instructions that, when executed, cause a programmable processor to:

control an implantable stimulation device to apply first electrical stimulation to at least a portion a first genitofemoral nerve of a patient at a point prior to the first genitofemoral nerve entering a first inguinal canal of the patient, and

control the implantable stimulation device to apply second electrical stimulation to at least a portion of a second genitofemoral nerve of the patient at a point after the second genitofemoral nerve exits a second inguinal canal of the patient,

wherein each of the first and second electrical stimulation is selected to alleviate pelvic pain of the patient.