Electrode contact configurations for cuff leads

• US 8,423,157 B2
• Filed: 05/24/2011
• Issued: 04/16/2013
• Est. Priority Date: 03/30/2006
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Moffitt, Michael Adam, Carbunaru, Rafael, Jaax, Kristen N., Whitehurst, Todd K.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Morales, Jon Eric C
• Application Number:
  US13/114,898
• Publication Number:
  US 20110224744A1
• Time in Patent Office: 693 Days
• Field of Search: 607/45, 607/118, 607/2
• US Class Current: 607/118
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor

Abstract

A stimulation system is disclosed that may include a stimulator unit coupled to electrode contacts on a cuff. In one embodiment, the cuff may be placed at least partially around a nerve. The stimulation system may include at least two electrode contacts disposed on the cuff such that a distance between the at least two electrode contacts various along a length of the electrode contacts. In another embodiment, a plurality of electrode contacts are disposed on the cuff such that distances between at least one electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the at least one electrode contact are different. The stimulator unit may also be implantable.

Claims

1. A stimulation system for a nerve, comprising:

a cuff configured and arranged to be placed, at least partially, around the nerve;

a plurality of electrode contacts disposed on the cuff, the plurality of electrode contacts comprising a first electrode contact, a second electrode contact adjacent the first electrode contact, a third electrode contact adjacent the second electrode contact, and a fourth electrode contact adjacent the third electrode contact, such that

     1) a distance between the first electrode contact and the second electrode contact,

     2) a distance between the second electrode contact and the third electrode contact, and

     3) a distance between the third electrode contact and the fourth electrode contact are all different from each other; and

a stimulator unit electrically coupled to the plurality of electrode contacts and configured and arranged for selecting two of the plurality of electrode contacts and providing stimulation to adjacent tissue using the two of the plurality of electrode contacts.

2. The stimulation system of claim 1, wherein the distances between the first, second, third, and fourth electrode contacts are selected, based in part, on another distance, the other distance being between the nerve and a point on the first electrode contact.

3. The stimulation system of claim 1, wherein, electrode contacts within the plurality of electrode contacts are arranged within a plurality of electrode contact arrays along the cuff, wherein the distances between one electrode contact array and each electrode contact array immediately adjacent to the one electrode contact array are different.

4. The stimulation system of claim 1, wherein the first electrode contact within the plurality of electrode contacts has a shorter length than at least one of the electrode contacts immediately adjacent to the first electrode contact.

5. The stimulation system of claim 1, the stimulator unit is arranged to provide a pre-pulse prior to providing electrical signals for stimulation of a nerve via the plurality of electrode contacts, wherein the pre-pulse does not stimulate the nerve.

6. The stimulation system of claim 1, wherein the cuff comprises a first portion that is curved and a second portion that is flat and attached to the first portion, wherein the cuff is configured and arranged so that both the first and second portions are disposed around the nerve.

7. The stimulation system of claim 6, wherein the curved portion has a shape of a half cylinder.

8. The stimulation system of claim 6, further comprising a third portion that is flat and attached to the first portion, wherein the second portion extends from a first end of the first portion and the third portion extends from a second end of the first portion, wherein the second end is opposite the first end.

9. The stimulation system of claim 6, wherein the second portion extends below the first portion.

10. A stimulation system for a nerve, comprising:

a cuff configured and arranged to be placed, at least partially, around the nerve;

a plurality of electrode contacts disposed on the cuff such that distances between a first electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the first electrode contact are different; and

a stimulator unit electrically coupled to the plurality of electrode contacts and configured and arranged for selecting two of the plurality of elements and providing stimulation to adjacent tissue using the two of the plurality of electrodes, wherein the plurality of electrode contacts further comprises at least two groupings of electrode contacts within the plurality of electrode contacts, wherein distances between one electrode contact within one of the at least two groupings and each electrode contact immediately adjacent to the one electrode contact within the same grouping are different.

11. The stimulation system of claim 10, wherein each electrode contact within one of the at least two groupings of electrode contacts is configured to operate independent of another electrode contact within the same grouping.

12. The stimulation system of claim 10, wherein each electrode contact within one of the at least two groupings of electrode contacts is configured to be electrically coupled together with each electrode contact within the same grouping to operate collectively.

13. A method of stimulating a nerve, the method comprising:

disposing a cuff, at least partially, around the nerve, the cuff having a plurality of electrode contacts disposed on the cuff such that a distance between a first electrode contact within the plurality of electrode contacts and at least one electrode contact immediately adjacent to the first electrode contact varies along a length of the first electrode contact;

coupling the cuff to a stimulator unit; and

providing electrical signals from the stimulator unit to a pair of the electrode contacts of the cuff to stimulate the nerve.

14. The method of claim 13, wherein, the nerve is a vagus nerve and disposing the cuff around the nerve comprises disposing the cuff around the vagus nerve.

15. The method of claim 13, wherein the nerve comprises a cavernous nerve and disposing the cuff around the nerve comprises disposing the cuff around a neurovascular bundle comprising the cavernous nerve.

16. The method of claim 15, wherein the cuff comprises a first portion that is curved and a second portion that is flat and wherein disposing the cuff, at least partially, around the nerve comprises disposing the cuff around the cavernous nerve with the second portion disposed between the cavernous nerve and a rectum.

17. The method of claim 13, further comprising providing a pre-pulse prior to providing the electrode signals to the electrode contacts to stimulate the nerve, wherein the pre-pulse does not stimulate the nerve.

18. The method of claim 13, wherein the cuff comprises a first portion that is curved and a second portion that is flat and wherein disposing the cuff, at least partially, around the nerve comprises disposing the first portion of the cuff over a region of the nerve and disposing the second portion of the cuff beneath the region of the nerve.

19. The method of claim 18, wherein the cuff comprises a third portion that is curved and wherein disposing the cuff, at least partially, around the nerve comprises disposing the third portion of the cuff beneath the region of the nerve.