Leak-compensated respiratory mechanics estimation in medical ventilators
First Claim
1. A method of compensating for leakage in a ventilation system during delivery of gas from a medical ventilator to a patient comprising:
- monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system;
modeling, by the medical ventilator, leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system;
estimating a leak-compensated instantaneous lung flow of gas inhaled or exhaled by the patient based on the one or more measurements, the first leakage component and second leakage component; and
using the leak-compensated lung flow and a predetermined respiratory mechanics model to estimate at least one of a leak-compensated lung compliance and a leak-compensated lung resistance.
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Abstract
This disclosure describes systems and methods for compensating for leakage when determining the respiratory mechanics of a patient during delivery of gas from a medical ventilator to a patient. The systems and methods include monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system. The leakage is modeled using a predetermined leakage model. A leak-compensated instantaneous lung flow of gas inhaled or exhaled by the patient is estimated. Using the leak-compensated lung flow and a predetermined respiratory mechanics model, the respiratory mechanics of a patient may be estimated including at least one of a leak-compensated lung compliance and a leak-compensated lung resistance. The method may include using a dynamic respiratory mechanics model or a static respiratory mechanics model that requires use of a pause maneuver to collect the necessary data.
659 Citations
14 Claims
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1. A method of compensating for leakage in a ventilation system during delivery of gas from a medical ventilator to a patient comprising:
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monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system; modeling, by the medical ventilator, leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system; estimating a leak-compensated instantaneous lung flow of gas inhaled or exhaled by the patient based on the one or more measurements, the first leakage component and second leakage component; and using the leak-compensated lung flow and a predetermined respiratory mechanics model to estimate at least one of a leak-compensated lung compliance and a leak-compensated lung resistance. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of compensating for leakage in a ventilation tubing system during delivery of gas from a medical ventilator to a patient comprising:
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identifying, by the medical ventilator, an inelastic leakage in the ventilation system as a first function of at least one of a pressure measurement and a flow measurement in the ventilation tubing system; identifying, by the medical ventilator, an elastic leakage in the ventilation system as a second function of at least one of the pressure measurement and the flow measurement in the ventilation tubing system; estimating circuit compliance and circuit resistance of the ventilation tubing system; and estimating one or more of a lung compliance of the patient and a lung resistance of the patient based on the inelastic leakage, the elastic leakage, the circuit compliance, circuit resistance and the at least one of the pressure measurement and the flow measurement in the ventilation system. - View Dependent Claims (13, 14)
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Specification