Computer system and method for training, certifying or monitoring human clinical raters
First Claim
1. A method comprising:
- receiving one or more rater inputs reflecting the rater'"'"'s clinical evaluation of a severity of a previously diagnosed condition in one or more subjects;
receiving one or more severity scores for the previously diagnosed condition in the one or more subjects, wherein said severity scores have been calculated by;
(a) presenting a first question to the subject and receiving a first input from the subject in response thereto;
(b) based on the first input, selecting a second question from a plurality of questions;
(c) presenting the selected second questions to the subject and receiving a second input from the subject in response thereto; and
(d) based on one or more inputs received from the subject, determining in accordance with a clinical rating scale the severity score for a previously diagnosed condition in the subject; and
determining, via a processor, whether the one or more rater inputs are in accordance with the one or more severity scores, respectively.
18 Assignments
0 Petitions
Accused Products
Abstract
A method and system are disclosed for computerized training, monitoring, certification or re-certification of human raters in clinical trials. The invention provides an interactive computerized interview that can be compared scores obtained by human raters to monitor and train clinical raters on a continuing basis in order to reduce rater drift and variance during clinical trials. Remediation can be automatically flagged or provided to improve a deviating rater'"'"'s performance. Computerized assessment of symptom severity is provided without the need for human clinical raters. The system and method enable screening of prospective patients for inclusion or exclusion from a clinical trial by automatically obtaining computerized ratings of symptom severity.
22 Citations
19 Claims
-
1. A method comprising:
-
receiving one or more rater inputs reflecting the rater'"'"'s clinical evaluation of a severity of a previously diagnosed condition in one or more subjects; receiving one or more severity scores for the previously diagnosed condition in the one or more subjects, wherein said severity scores have been calculated by; (a) presenting a first question to the subject and receiving a first input from the subject in response thereto; (b) based on the first input, selecting a second question from a plurality of questions; (c) presenting the selected second questions to the subject and receiving a second input from the subject in response thereto; and (d) based on one or more inputs received from the subject, determining in accordance with a clinical rating scale the severity score for a previously diagnosed condition in the subject; and determining, via a processor, whether the one or more rater inputs are in accordance with the one or more severity scores, respectively. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
-
-
11. A method for monitoring performance of a clinical rater participating in a clinical trial comprising:
-
receiving a rater input reflecting the rater'"'"'s clinical evaluation of a severity of a previously diagnosed condition in a subject; receiving a calculated severity score for the previously diagnosed condition in the subject, wherein said severity scores have been calculated by; (a) presenting a first question to the subject and receiving a first input from the subject in response thereto; (b) based on the first input, selecting a second question from a plurality of questions; (c) presenting the selected second questions to the subject and receiving a second input from the subject in response thereto; and (d) based on one or more inputs received from the subject, determining in accordance with a clinical rating scale the calculated severity score for a previously diagnosed condition in the subject; and comparing, via a processor, the rater input with the calculated severity score, including determining if the rater input deviates from the calculated severity score by more than a given threshold. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
-
Specification