C-shaped cross section tubular ophthalmic implant for reduction of intraocular pressure in glaucomatous eyes and method of use

• US 8,425,450 B2
• Filed: 09/08/2010
• Issued: 04/23/2013
• Est. Priority Date: 10/18/2000
• Status: Active Grant

• Current Assignee: AQ BioMed, LLC
• Original Assignee: Aqueous Biomedical, Inc.
• Inventors: Wilcox, Michael J.
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US12/877,809
• Publication Number:
  US 20110098627A1
• Time in Patent Office: 958 Days
• Field of Search: 604 27- 29, 604 31- 34, 604/521, 604/294, 606/101, 606/166, 606/153
• US Class Current: 604/8
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

An implant may be used for implantation into tissue of a body. The implant includes an elongated conduit and a loop. The elongated conduit has an interior passageway for conducting fluid. The loop has an interior circumference with a fluid conducting channel formed therein. The channel is interconnected with the interior passageway for delivery of fluid between the channel and the interior passageway.

Claims

1. A tube for implantation into the eye for conducting aqueous humor from a chamber of the eyeball to subconjunctival tissue comprising:

an elongated fluid conducting conduit having distal and proximate ends, a sidewall and an interior passageway and at least one longitudinally extending opening in the sidewall that exposes the interior passageway;

wherein said longitudinally extended opening is a nidus configured for formation of a cylindrical aqueous filtration bleb.

2. The tube of claim 1, further comprising at least one releasable ligature circumscribing the conduit.

3. The tube of claim 2, wherein a releasable ligature is positioned between the proximal end and the longitudinal opening.

4. The tube of claim 1, further comprising at least one anchoring structure for attaching the tube to the sclera to prevent the tube from migrating from its placement site.

5. The tube of claim 4, wherein the anchor structure comprises a plurality of conduit furcations.

6. The tube of claim 5, wherein the furcations are disposed at the distal end of the conduit.

7. The tube of claim 1, comprising a plurality of longitudinal openings.

8. A method of conducting aqueous humor from a chamber of the eyeball to subconjunctival tissue comprising:

implanting into the eye a tube comprising an elongated fluid conducting conduit having distal and proximate ends, a sidewall and an interior passageway and at least one longitudinally extending opening in the sidewall that exposes the interior passageway, wherein said longitudinally extended opening is a nidus configured for formation of a cylindrical aqueous filtration bleb; and

allowing scar tissue to form at the exposed interior passageway of the longitudinally extended opening.

9. The method of claim 8, further comprising removing at least one releasable ligature circumscribing the conduit.

10. The method of claim 9, wherein the releasable ligature is positioned between the proximal end and the longitudinal opening and releasing the ligature causes aqueous humor to flow from the chamber of the eyeball through the elongated fluid conducting conduit to form a cylindrical aqueous filtration bleb in the subconjunctival tissue.

11. The method of claim 10, further comprising releasing a second ligature positioned between the longitudinal opening and a second longitudinal opening causing aqueous humor to flow from the chamber of the eyeball through the elongated fluid conducting conduit to form a second cylindrical aqueous filtration bleb in the subconjunctival tissue.

12. The method of claim 9, wherein the at least one portion of sidewall forms a nidus forming a cylindrical bleb when aqueous humor flows through the longitudinal opening positioned at or near the portion of the sidewall.

13. The method of claim 8, further comprising

a tube with at least one anchoring structure, wherein scar tissue is allowed to form at the at least one anchoring structure attaching the tube to sclera to prevent the tube from migrating from its placement site.

14. The method of claim 13, wherein the anchor structure comprises a plurality of conduit furcations.

15. The method of claim 14, wherein the furcations are disposed at the distal end of the conduit.

16. The method of claim 8, wherein the tube further comprises at least one portion of the sidewall extending outward from the tube and positioned at or near the at least one longitudinal opening.

17. The method of claim 8, further comprising allowing aqueous humor to filter through the bleb.