Aneurysm occlusion device containing bioactive and biocompatible copolymer shell and a liquid embolic agent
First Claim
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1. An endovascular medical device comprising:
- a polymeric member defining an interior chamber; and
a liquid embolic agent, the liquid embolic agent being capable of solidifying upon activation, wherein the polymeric member is constructed from a copolymer comprising a biocompatible polyurethane and a bioactive polysaccharide, wherein the bioactive polysaccharide is incorporated into the biocompatible polyurethane backbone of the copolymer.
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Abstract
An endovascular device for occluding a vascular aneurysm is disclosed. The device includes a polymeric shell member that, in one embodiment, may be constructed from a bioactive and biocompatible polyurethane-diol-glycosaminoglycan copolymer, and a liquid embolic agent. The copolymer is sufficiently flexible and strong for endovascular delivery into a vascular aneurysm and for use as a polymeric shell for receiving the liquid embolic agent. Upon activation inside of the polymeric shell within the aneurysm, the liquid embolic agent solidifies enabling biological isolation of the aneurysm and improved patient outcomes.
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Citations
13 Claims
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1. An endovascular medical device comprising:
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a polymeric member defining an interior chamber; and a liquid embolic agent, the liquid embolic agent being capable of solidifying upon activation, wherein the polymeric member is constructed from a copolymer comprising a biocompatible polyurethane and a bioactive polysaccharide, wherein the bioactive polysaccharide is incorporated into the biocompatible polyurethane backbone of the copolymer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification