Flavored colonic cleansing system

• US 8,425,944 B2
• Filed: 07/15/2011
• Issued: 04/23/2013
• Est. Priority Date: 03/03/2006
• Status: Expired due to Fees

• Current Assignee: C. B. Fleet Company Incorporated
• Original Assignee: C. B. Fleet Company Incorporated
• Inventors: Caswell, Michael L.
• Primary Examiner(s): Alstrum-Acevedo, James H.
• Assistant Examiner(s): CHOI, FRANK I
• Application Number:
  US13/184,007
• Publication Number:
  US 20110274765A1
• Time in Patent Office: 648 Days
• Field of Search: None
• US Class Current: 424/606
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/70 Carbohydrates; Sugars; Derivatives thereof sorbitol A61K31/047
• CPC Class Codes: A61K 33/42 Phosphorus; Compounds thereof
• CPC Class Codes: A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 1/10 Laxatives
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A kit for colonic cleansing includes a phosphate salt laxative, a flavorant, and an oral rehydration mixture. The flavorant includes aspartame and a citrate, and the oral rehydration mixture includes sodium and a glucose containing saccharide. The kit may be used for a colonic cleansing procedure by combining the phosphate salt laxative and the flavorant to provide a flavored laxative liquid, orally administering to a subject the flavored laxative liquid, and orally administering to the subject an oral rehydration liquid.

Claims

1. A kit for colonic cleansing, comprising:

a phosphate salt laxative, comprising from 0.4 to 1 gram/mL of monobasic sodium phosphate and from 0.13 to 0.25 gram/mL of dibasic sodium phosphate;

a flavorant, comprising aspartame, maltodextrin, acesulfame potassium and a citrate, wherein about 45 mL of the phosphate salt laxative is present for each 2-6 grams of the flavorant, and

an oral rehydration mixture, comprising sodium, and a glucose containing saccharide.

2. The kit of claim 1, where the phosphate salt laxative comprises 0.48 gram/mL of monobasic sodium phosphate and 0.18 gram/mL of dibasic sodium phosphate.

3. The kit of claim 1, where the phosphate salt laxative is present as a solid.

4. The kit of claim 1, where the phosphate salt laxative is present as an aqueous liquid in at least one bottle.

5. The kit of claim 4, where the phosphate salt laxative is present as an aqueous liquid in at least two bottles, each bottle comprising from 10 to 75 mL of the liquid.

6. The kit of claim 4, where the phosphate salt laxative is present as an aqueous liquid in at least six bottles, each bottle comprising from 10 to 75 mL of the liquid.

7. The kit of claim 1, where the flavorant further comprises a flavoring selected from the group consisting of natural fruit flavors, artificial fruit flavors, and combinations thereof.

8. The kit of claim 1, where the citrate comprises citric acid and potassium citrate;

and the flavorant further comprises natural flavor, lemon juice solids, and artificial color.

9. The kit of claim 1, where the flavorant further comprises ascorbic acid or a salt thereof.

10. The kit of claim 1, where the flavorant is present as an aqueous liquid.

11. The kit of claim 1, where the flavorant is present as a solid.

12. The kit of claim 11, where the flavorant is present as a powder in at least one packet.

13. The kit of claim 12, where the flavorant is present as a powder in at least two packets, each packet comprising from 1 to 10 grams of the powder.

14. The kit of claim 1, where the oral rehydration mixture comprises a ratio of glucose containing saccharide to sodium of 0.1 to 15 g:

0.1 to 200 mmol.

15. The kit of claim 1, where the oral rehydration mixture comprises a ratio of glucose containing saccharide to sodium of 1 to 10 g:

2 to 100 mmol.

16. A method for colonic cleansing using the kit of claim 1, comprising:

combining the phosphate salt laxative and the flavorant to provide a flavored laxative liquid;

orally administering to a subject the flavored laxative liquid; and

orally administering to the subject an oral rehydration liquid,

the oral rehydration liquid comprising sodium and a glucose containing saccharide.

17. A kit for colonic cleansing, comprising:

at least two bottles, each comprising about 45 mL of a phosphate salt laxative, the phosphate salt laxative comprising

water,

from 0.4 to 1 gram/mL of monobasic sodium phosphate, and

from 0.13 to 0.25 gram/mL of dibasic sodium phosphate

at least two packets, each comprising from 2-6 grams of a powdered flavorant, the flavorant comprising

aspartame, maltodextrin, acesulfame potassium and a citrate, wherein about 45 mL of the phosphate salt laxative is present for each 2-6 grams of the flavorant, and at least one packet comprising from 200 to 400 grams of a powdered oral rehydration mixture, the oral rehydration mixture comprising sodium, and a glucose containing saccharide.