Sequenced therapy protocols for an implantable medical device

• US 8,428,731 B2
• Filed: 10/27/2005
• Issued: 04/23/2013
• Est. Priority Date: 10/27/2005
• Status: Active Grant

• Current Assignee: LivaNova USA, Inc. (LivaNova Plc)
• Original Assignee: Cyberonics, Inc
• Inventors: Armstrong, Randolph
• Primary Examiner(s): Patel, Niketa
• Assistant Examiner(s): ALTER, ALYSSA MARGO
• Application Number:
  US11/260,836
• Publication Number:
  US 20070100391A1
• Time in Patent Office: 2,735 Days
• Field of Search: 607/2, 607/45
• US Class Current: 607/45
• CPC Class Codes: A61N 1/36053 adapted for vagal stimulation A61N1/36114 takes precedence
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer
• CPC Class Codes: A61N 1/37264 Changing the program; Upgrading firmware

Abstract

In one embodiment of the invention, a method comprises (a) implementing a first therapy in an implantable medical device (IMD) from a programmed sequence of therapies for a first time period, (b) implementing a second therapy from the sequence in the IMD for a second time period following the first time period, and repeating (a) and (b).

Claims

1. A method of operating an implantable medical device (IMD) to provide neurostimulation, the method comprising:

operating a first therapy program from a therapy sequence for a first therapy time, wherein a plurality of neurostimulation therapy programs comprising the therapy sequence are stored in the IMD before any of the neurostimulation therapy programs are operated;

the IMD automatically operating a second therapy from the therapy sequence in the IMD for a second therapy time following the first therapy time; and

the IMD automatically repeating the therapy programs in the therapy sequence.

2. The method of claim 1 wherein the first therapy time and the second therapy time are substantially the same.

3. The method of claim 1 wherein the first therapy time and the second therapy time are different.

4. The method of claim 1 wherein the first and second therapy times are determined by an elapsed time, an indication from outside the IMD, or combination thereof.

5. The method of claim 1 wherein the plurality of neurostimulation therapy programs are stored by programming a plurality of parameters to define each neurostimulation therapy program in the therapy sequence, and wherein the plurality of parameters comprises at least two parameters selected from a current amplitude, a pulse width, a frequency, an on time, an off time, a therapy program time, a total therapy sequence time, or combinations thereof.

6. The method of claim 1 wherein the first therapy program is operated automatically by the IMD.

7. The method of claim 1 further comprising:

the IMD receiving a wireless signal from an external system, the wireless signal instructing the IMD to continue operating a particular therapy program that is operating when the signal is received, and to discontinue automatically repeating the therapy programs in the therapy sequence.

8. The method of claim 1 further comprising:

the IMD receiving a wireless signal from an external system, the wireless signal instructing the IMD to discontinue automatically repeating the therapy programs in the therapy sequence, and to begin operating a first particular therapy program that was operating immediately preceding a second particular therapy program that was operating when the signal was received.

9. The method of claim 1 further comprising:

(d) operating a third therapy program from the therapy sequence in the IMD for a third therapy time following the second therapy time.

21. The method of claim 1 further comprising:

interrupting the repeating of the therapy programs; and

operating a particular therapy program selected from the therapy sequence.

22. The method of claim 21 wherein the particular therapy program is selected from a current therapy program in the therapy sequence, wherein the current therapy program is the therapy program operating when repeating of the therapy programs is interrupted;

a previous therapy program operating immediately prior to the current therapy program;

and a last therapy program in the therapy sequence.

23. The method of claim 21 wherein subsequent therapy programs in the therapy sequence operate with a greater current magnitude than an immediately preceding therapy program.

10. A method, comprising:

operating a first therapy program in an implantable neurostimulator, wherein the implantable neurostimulator stores the first therapy program and a plurality of additional therapy programs;

automatically causing the implantable neurostimulator to sequence through the plurality of additional therapy programs in a therapy sequence; and

after the therapy sequence, automatically operating and continuing the first therapy program in the neurostimulator and not automatically repeating automatically causing the implantable neurostimulator to sequence through the plurality of additional therapy programs in the therapy sequence.

11. The method of claim 10 wherein the therapy sequence comprises the first therapy program.

12. The method of claim 10 wherein the first therapy program and each of the plurality of additional therapy programs comprise a plurality of parameters selected from a current amplitude, a pulse width, a frequency, an on time, an off time, a therapy program time, a total therapy sequence time, or combinations thereof.

13. An implantable medical device (IMD), comprising:

an electrical signal generator configured to provide an electrical signal to stimulate a neural structure of a patient;

a controller coupled to the electrical signal generator, the controller configured to cause a plurality of therapy programs to be operated by the electrical signal generator in an automatic, cyclically-repeated sequence; and

wherein the plurality of therapy programs are stored in the IMD before the automatic, cyclically-repeated sequence begins.

14. The implantable medical device of claim 13 wherein the controller automatically sequences through the plurality of therapy programs, each therapy program being operated for a therapy sequence time.

15. The implantable medical device of claim 14 wherein the therapy sequence time is the same for each therapy program.

16. The implantable medical device of claim 13 further comprising a user-input sense device and wherein the controller sequences from one therapy program to a next therapy program when indicated by a user input.

17. The implantable medical device of claim 13 wherein the controller implements each of the plurality of therapy programs for an amount of time that is a programmed time for each therapy.

18. The implantable medical device of claim 13 wherein each of the plurality of therapy programs comprises a plurality of parameters selected a current amplitude, a pulse width, a frequency, an on time, an off time, a therapy program time, a total therapy sequence time, or combinations thereof.

19. An implantable medical device, comprising:

an electrical signal generator configured to provide an electrical signal to stimulate a neural structure of a patient;

a controller coupled to the electrical signal generator, the controller configured to automatically cause a first therapy program operated by the electrical signal generator to be interrupted, a plurality of therapy programs to subsequently be implemented in programmed sequence automatically by the electrical signal generator, and the first therapy program to again be operated automatically; and

storage internal to the implantable medical device in which the first therapy program and the plurality of therapy programs are pre-stored.

20. The implantable medical device of claim 19 wherein the controller automatically sequences through the plurality of therapy programs.