Method and device for detecting air in a fluid system, in particular in an extracorporeal blood circuit of a blood treatment device

• US 8,430,834 B2
• Filed: 09/25/2007
• Issued: 04/30/2013
• Est. Priority Date: 09/26/2006
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Deutschland GmbH (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius Medical Care Deutschland GmbH (Fresenius SE & Co. KGaA)
• Inventors: Kopperschmidt, Pascal
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US12/443,000
• Publication Number:
  US 20090247926A1
• Time in Patent Office: 2,044 Days
• Field of Search: 604 401- 616, 604 27- 29, 604 65- 67, 600485-487, 73/40, 73/405.A, 73/405.R, 735/93
• US Class Current: 604/6.11
• CPC Class Codes: A61M 1/3626 Gas bubble detectors
• CPC Class Codes: A61M 1/3639 Blood pressure control, pressure transducers specially adapted therefor
• CPC Class Codes: A61M 5/365 Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626

Abstract

The present invention relates to a method and to a device for detecting the entry of air in a fluid system, in particular in an extracorporeal blood circuit of a blood treatment device comprising an arterial branch leading to the blood treatment unit and a venous branch leading from said blood treatment unit. Periodic fluctuations in the fluid system, in particular in the arterial tube, are measured upstream of the blood pump arranged in said arterial tube. The measured periodic pressure signal is analyzed spectrally in a system of functions, in particular a system of orthogonal functions, for example sine and cosine functions and the entry of air is deduced if at least one of the coefficients of the functions exceeds or falls below predefined threshold values.

Claims

1. A method for detecting the ingress of air into a system for liquid comprising:

measuring and analyzing a pressure signal in the liquid;

spectrally breaking down the measured pressure signal into at least one function, said at least one function having at least one coefficient;

monitoring the at least one coefficient of the at least one function;

comparing the at least one coefficient of the at least one function to respective preset limiting values; and

determining that there has been an ingress of air into the system for liquid if at least one of the coefficients of the at least one function exceeds or drops below the respective preset limiting values.

2. The method according to claim 1, wherein the at least one function is a system of orthogonal functions.

3. The method according to claim 2, wherein the orthogonal functions are sine functions and cosine functions.

4. The method according to claim 1, wherein the respective preset limiting values define a limiting value range having an upper limiting value and a lower limiting value, the method further comprising:

determining there has been an ingress of air into the system for liquid if at least one of the coefficients of the at least one function exceeds the upper limiting value or drops below the lower limiting value.

5. The method according to claim 4, wherein a plurality of coefficients of the at least one function are each compared with an upper and a lower limiting value, the method further comprising:

determining there has been an ingress of air into the system for liquid if all of the plurality of coefficients of the at least one function exceed the upper limiting value or drop below the lower limiting value.

6. The method according to claim 5, wherein the at least one function is a plurality of functions, the method further comprising:

determining there has been an ingress of air into the system for liquid if the plurality of coefficients of the plurality of the functions exceed the upper limiting value or drop below the lower limiting value.

7. The method according to claim 1, wherein the system comprises a pump, the method further comprising:

measuring the pressure signal upstream of the pump.

8. The method according to claim 7, wherein the pump is located in a conduit, further comprising:

measuring the pressure signal in the conduit.

9. The method according to claim 1, wherein the system comprises an extra-corporeal blood circuit of a blood-treating apparatus comprising:

an arterial segment leading to the blood-treating unit and a venous segment leading from the blood-treating unit, the method further comprising;

measuring and analyzing the pressure signal in the arterial segment or the venous segment of the extra-corporeal blood circuit.

10. The method according to claim 9, wherein a blood pump is located in the arterial segment, the method further comprising:

measuring the pressure signal in the arterial segment, upstream of the blood pump.

11. A system for detecting the ingress of air into a system for liquid, comprising:

means for measuring a pressure signal in the system for liquid; and

means for analyzing the measured pressure signal comprising;

means for spectrally breaking down the measured pressure signal into at least one function, said at least one function having at least one coefficient; and

means for monitoring the at least one coefficient of the at least one function and comparing the at least one coefficient to respective preset limiting values, configured such that an ingress of air into the system for liquid is determined if at least one of the coefficients of the at least one function exceeds or drops below the respective preset limiting values.

12. The system according to claim 11, wherein the at least one function is a system of orthogonal functions.

13. The system according to claim 12, wherein the orthogonal functions are sine functions and cosine functions.

14. The system according to claim 11, wherein the means for monitoring further comprises:

means for comparing configured such that at least one of the coefficients is compared with an upper limiting value and a lower limiting value, and an ingress of air into the system for liquid is determined if the at least one coefficient of the at least one function exceeds the upper limiting value or drops below the lower limiting value.

15. The system according to claim 14, wherein the means for comparing are configured such that a plurality of coefficients of the at least one function are each compared with an upper limiting value and a lower limiting value, and an ingress of air into the system for liquid is determined if all of the plurality of coefficients of the functions exceed the upper limiting value or drop below the lower limiting value.

16. The system according to claim 11, further comprising a pump, wherein the means for measuring pressure is located upstream of the pump.

17. The system according to claim 16, wherein the pump is located in a conduit and the means for measuring pressure measures pressure in the conduit.

18. The system according to claim 11 wherein the system further comprises:

an extra-corporeal blood circuit of an extra-corporeal blood-treating apparatus comprising an arterial segment leading to a blood-treating unit and a venous segment leading from the blood-treating unit, the means for measuring pressure being located in the arterial segment or the venous segment of the extra-corporeal blood circuit.

19. The system according to claim 18, further comprising a blood pump located in the arterial segment, wherein the means for measuring pressure is located upstream of the blood pump.

20. An extra-corporeal blood-treating apparatus comprising:

an extra-corporeal blood circuit which has an arterial segment leading to a blood-treating unit and a venous segment leading from the blood-treating unit, wherein the blood-treating apparatus has a system for detecting the ingress of air into the extra-corporeal blood circuit comprising;

means for measuring a pressure signal in the system for liquid; and

means for analyzing the measured pressure signal comprising;

means for spectrally breaking down the measured pressure signal measured into at least one function, said at least one function having at least one coefficient;

means for monitoring the at least one coefficient of the at least one function and comparing the at least one coefficient to respective preset limiting values, configured such that an ingress of air into the system for liquid is determined if at least one of the coefficients of the at least one function exceeds or drops below the respective preset limiting values.

21. A system for detecting the ingress of air into a system for liquid, comprising:

a measurement system configured to measure a pressure signal in the system for liquid; and

an analysis system configured to analyze the measured pressure signal comprising;

a function system configured to spectrally break down the measured pressure signal into at least one function, said at least one function having at least one coefficient; and

a monitoring system configured to monitor the at least one coefficient of the at least one function and compare the at least one coefficient to respective preset limiting values,

wherein the monitoring system is configured such that an ingress of air into the system for liquid is determined if at least one of the coefficients of the at least one function exceeds or drops below the respective preset limiting values.

22. The system according to claim 21, wherein the at least one function is a system of orthogonal functions.

23. The system according to claim 22, wherein the orthogonal functions are sine functions and cosine functions.

24. The system according to claim 21, wherein the monitoring system further comprises:

a comparison system configured such that at least one of the coefficients is compared with an upper limiting value and a lower limiting value, and an ingress of air into the system for liquid is determined if the at least one coefficient of the at least one function exceeds the upper limiting value or drops below the lower limiting value.

25. The system according to claim 24, wherein the comparison system is configured such that a plurality of coefficients of the at least one function are each compared with an upper limiting value and a lower limiting value, and an ingress of air into the system for liquid is determined if all of the plurality of coefficients of the functions exceed the upper limiting value or drop below the lower limiting value.

26. The system according to claim 21, further comprising a pump, wherein the measurement system is located upstream of the pump.

27. The system according to claim 26, wherein the pump is located in a conduit and the measurement system measures pressure in the conduit.

28. The system according to claim 21 wherein the system further comprises:

an extra-corporeal blood circuit of an extra-corporeal blood-treating apparatus comprising an arterial segment leading to a blood-treating unit and a venous segment leading from the blood-treating unit, the measurement system being located in the arterial segment or the venous segment of the extra-corporeal blood circuit.

29. The system according to claim 28, further comprising a blood pump located in the arterial segment, wherein the measurement system is located upstream of the blood pump.