Vascular occlusion device

• US 8,430,934 B2
• Filed: 09/01/2004
• Issued: 04/30/2013
• Est. Priority Date: 03/01/2002
• Status: Active Grant

• Current Assignee: Regents of The University of Minnesota (University of Minnesota)
• Original Assignee: Regents of The University of Minnesota (University of Minnesota)
• Inventors: Das, Gladwin S.
• Primary Examiner(s): Severson, Ryan
• Assistant Examiner(s): MILES, JONATHAN WADE
• Application Number:
  US10/931,937
• Publication Number:
  US 20050070957A1
• Time in Patent Office: 3,163 Days
• Field of Search: 606/213, 606/215, 606/232, 623/23.7, 623/23.72, 600/31, 600/32, 604/41, 604/42
• US Class Current: 623/23.72
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12131 characterised by the type of occluding device
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00628 T-shaped occluders

Abstract

An occlusion device includes a pair of connected members configured for being situated on opposing sides of a hole in a tissue, wherein the pair of connected members are formed of a material which is bioadsorbable to the tissue. The pair of connected members can include a non-metallic skeleton.

Claims

1. An occlusion device comprising:

first and second disk members which are connected together, each of the first and second disk members having a self-expanding, non-metallic structure including a plurality of integral rib members which are flexible so as to be compressible within a catheter and are biased towards an open position to automatically expand the disk members when the disk members are removed from the catheter, wherein one or more of the rib members are thinner towards an outer end of the rib member such that a periphery area of each disk member is more flexible than an inner area of each disk member; and

a collapsible central rim connecting the first and second disk members together, the collapsible central rim defining a central occluding area located within the central rim that is dimensioned to extend across a diameter of a hole to occlude the hole, wherein the central rim has an outer periphery defining a membrane surface and a sinuous skeleton structure on the membrane surface extending around the outer periphery of the central rim.

2. The occlusion device of claim 1, wherein the occlusion device includes a bioabsorbable material.

3. The occlusion device of claim 2, wherein the bioabsorbable material includes polyglycolic acid.

4. The occlusion device of claim 2, wherein the bioabsorbable material includes polydioxanone.

5. The occlusion device of claim 2, wherein the bioabsorbable material includes polylactic acid.

6. The occlusion device of claim 2, wherein the bioabsorbable material includes polycaprolactone.

7. The occlusion device of claim 1, wherein the sinuous skeleton structure is configured to bias the central rim in an outward direction.

8. The occlusion device of claim 1, wherein each of the plurality of ribs are radially oriented on the first and second disk members.

9. The occlusion device of claim 1, wherein at least a portion of the plurality of ribs define a petal-shaped configuration.

10. The occlusion device of claim 1, wherein the sinuous skeleton structure located around the periphery of the central rim bias the periphery of the central rim against the tissue.

11. The occlusion device of claim 1, further including one or more holes formed in one of the disk members proximate a periphery of the disk member.

12. The occlusion device of claim 11, wherein each of the one or more holes are encircled by a portion of the rib members.

13. The occlusion device of claim 1, wherein the occlusion device is a one-piece integral device.

14. The occlusion device of claim 1, wherein the occlusion device is a one-piece integral device formed of a non-metallic material.

15. An occlusion device comprising:

a pair of disk members connected together at a central occluding area, wherein each of the pair of disk members includes a membrane flange having integral rib sections, and wherein the integral rib sections each include a plurality of ribs which extend radially along a surface of the membrane flange towards a periphery of the disk members, and one or more holes formed proximate the periphery of one of the disk members, wherein one or more of the ribs are thinner towards an outer end of the rib such that a periphery area of each disk member is more flexible than an inner area of each disk member, and wherein the central occluding area includes a collapsible central rim located around the central occluding area and connecting the first and second disks together in the central occluding area, the collapsible central rim dimensioned to extend across a diameter of a hole so that the central occluding area occludes the hole, and wherein the central rim has an outer periphery defining a membrane surface and a sinuous skeleton structure on the membrane surface extending around the outer periphery of the central rim.

16. The occlusion device of claim 15, wherein each of the disk members are adapted to be self-expanding.

17. The occlusion device of claim 15, wherein the occlusion device includes a bioabsorbable material.

18. The occlusion of claim 15, wherein the sinuous skeleton structure located around the periphery of the central rim biases the periphery of the central rim outward.

19. The occlusion device of claim 15, wherein each of the one or more holes are encircled by a portion of the rib members.

20. An occlusion device comprising:

first and second flanges which are connected together with a central occluding section located between the first and second flanges, wherein the central occluding section includes a collapsible central rim which is dimensioned to extend across a diameter of a hole in a tissue, and wherein each of the first and second flanges include a self-expanding, non-metallic structure including a membrane with a plurality of integral rib members located along a surface of the membrane and wherein the rib members are flexible so as to be compressible within a catheter and are biased towards an open position to automatically expand the flanges when the flanges are removed from the catheter, wherein one or more of the ribs are thinner towards an outer end of the rib such that a periphery area of each flange is more flexible than an inner area of each flange, and wherein the first and second flanges, the rib members, and the central occluding section are all formed as a one-piece integral unit formed from a bioabsorbable material, and wherein the central rim has an outer periphery defining a membrane surface and a sinuous skeleton structure on the membrane surface extending around the outer periphery of the central rim.

21. The occlusion device of claim 20, wherein the integral rib members extend radially towards a periphery of the flanges.

22. The occlusion device of claim 20, further including one or more holes formed proximate the periphery of one of the flanges.