Cyclopamine lactam analogs and methods of use thereof
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Abstract
The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancer.
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23 Claims
- 1. A compound of the formula:
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2. A pharmaceutical composition comprising a compound of the formula:
- 3. A method of treating cancer, which comprises administering to a subject in need thereof a therapeutically effective amount of a compound of the formula:
Specification