Implantable medical device
First Claim
Patent Images
1. An analyte measuring system comprising:
- an implantable medical device comprising;
an electrode connecting arrangement connectable to at least two implantable electrodes;
a signal source that generates a current or voltage signal and for applying said current or voltage signal to a tissue using said at least two implantable electrodes;
a signal measurer that measures a resulting voltage or current signal from said tissue sensed by said at least two implantable electrodes;
an impedance determiner that determines an impedance signal based on said generated current or voltage signal and said measured resulting voltage or current signal; and
a signal processor that generates an estimate of a concentration of an analyte in said tissue by making a spectral analysis of said impedance signal determined by said impedance determiner;
wherein said signal processor generates said estimate of said analyte concentration based on a ratio of an amplitude of said impedance signal at a first frequency and an amplitude of said impedance signal at a second frequency; and
wherein said signal processor generates said estimate of said analyte concentration based on a comparison of said ratio and a corresponding ratio determined by said signal processor based on a spectral analysis of a reference impedance signal determined based on a previously applied current or voltage signal and a previously measured resulting voltage or current signal.
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Abstract
An analyte measuring system has an implantable medical device having a signal source arranged for generating a current signal and electrodes for applying the current signal to a surrounding tissue in a subject body. The device measures a resulting voltage signal with the electrodes and calculates an impedance signal therefrom. The system comprises a signal processor arranged for generating an estimate of a concentration of an analyte in the tissue based on a spectrum analysis of the determined impedance signal.
10 Citations
11 Claims
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1. An analyte measuring system comprising:
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an implantable medical device comprising; an electrode connecting arrangement connectable to at least two implantable electrodes; a signal source that generates a current or voltage signal and for applying said current or voltage signal to a tissue using said at least two implantable electrodes; a signal measurer that measures a resulting voltage or current signal from said tissue sensed by said at least two implantable electrodes; an impedance determiner that determines an impedance signal based on said generated current or voltage signal and said measured resulting voltage or current signal; and a signal processor that generates an estimate of a concentration of an analyte in said tissue by making a spectral analysis of said impedance signal determined by said impedance determiner; wherein said signal processor generates said estimate of said analyte concentration based on a ratio of an amplitude of said impedance signal at a first frequency and an amplitude of said impedance signal at a second frequency; and wherein said signal processor generates said estimate of said analyte concentration based on a comparison of said ratio and a corresponding ratio determined by said signal processor based on a spectral analysis of a reference impedance signal determined based on a previously applied current or voltage signal and a previously measured resulting voltage or current signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An analyte estimating method comprising:
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generating a current or voltage signal; applying said current or voltage signal to a tissue using two implantable electrodes; sensing a resulting voltage or current signal from said tissue using two implantable electrodes; determining an impedance signal based on said generated current or voltage signal and said sensed resulting voltage or current signal; and generating an estimate of a concentration of an analyte in said tissue by making a spectral analysis of said impedance signal; wherein said generating an estimate of a concentration further comprises determining a ratio of an amplitude of said impedance signal at a first frequency and an amplitude of said impedance signal at a second frequency and comparing said ratio and a corresponding ratio based on a spectral analysis of a reference impedance signal determined based on a previously applied current or voltage signal and a previously measured resulting voltage or current signal.
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Specification