Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures
First Claim
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1. A neuro-stimulation system for a patient, comprising:
- an electrode array having an implantable support member configured to be implanted into a patient and a plurality of therapy electrodes carried by the support member,a pulse system operatively coupled to the therapy electrodes, the pulse system delivering a stimulus to the therapy electrodes; and
a controller operatively coupled to the pulse system, the controller including a computer operable medium containing instructions that generate command signals that define the stimulus delivered by the pulse system and determine a desired configuration for the therapy electrodes and/or a desired stimulus to be delivered to the therapy electrodes based upon feedback input to the controller, wherein (i) the feedback input reflects a measure of motor activity of the patient and (ii) the control employs a curve fitting operation to adjust stimulation parameters when operation of the pulse system is changed from a first frequency to a second frequency.
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Abstract
Test procedures for determining a neural stimulation threshold of a patient. In one embodiment, the procedure includes applying a test stimulation signal to the patient and monitoring the patient for a response to the test stimulation signal. The procedure can further include determining a first neural stimulation threshold and calculating a second neural stimulation threshold. The first neural stimulation threshold corresponds to the lowest intensity test stimulation signal that evokes a patient response. The second neural stimulation threshold corresponds to a treatment stimulation signal directed toward affecting a neural activity within the patient.
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Citations
18 Claims
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1. A neuro-stimulation system for a patient, comprising:
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an electrode array having an implantable support member configured to be implanted into a patient and a plurality of therapy electrodes carried by the support member, a pulse system operatively coupled to the therapy electrodes, the pulse system delivering a stimulus to the therapy electrodes; and a controller operatively coupled to the pulse system, the controller including a computer operable medium containing instructions that generate command signals that define the stimulus delivered by the pulse system and determine a desired configuration for the therapy electrodes and/or a desired stimulus to be delivered to the therapy electrodes based upon feedback input to the controller, wherein (i) the feedback input reflects a measure of motor activity of the patient and (ii) the control employs a curve fitting operation to adjust stimulation parameters when operation of the pulse system is changed from a first frequency to a second frequency. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. In a computer, a method of automatically determining a favorable neuro-stimulation program for a patient, comprising:
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applying an electrical stimulus having a plurality of stimulus parameters to a selected configuration of the therapy electrodes that have been installed at a target therapy site of a patient; sensing a response to the applied electrical stimulus at a sensing device that has been installed at a sense location of the patient; determining whether the response is within a desired range or an improvement over a previous sensed response from a different electrical stimulus and/or a different configuration of therapy electrodes; selecting an alternate configuration of therapy electrodes and/or an alternate electrical stimulus; repeating the applying, sensing, determining and selecting procedures using the alternate configuration of therapy electrodes and/or the alternate electrical stimulus; and choosing a configuration of therapy electrodes and/or an electrical stimulus corresponding to a sensed response that is within a desired range and/or provides a better result compared to other sensed responses; wherein the selecting procedure comprises computing an alternate stimulus parameter while maintaining a constant electrode configuration, and wherein computing the alternate stimulus parameter comprises correlating a plurality of different stimuli applied to the constant electrode configuration with corresponding sensed responses to determine a stimulus/response trend and estimating a new stimulus parameter that is expected to improve the efficacy according to the stimulus/response trend. - View Dependent Claims (16, 17, 18)
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Specification