Assessing residual insulin time

• US 8,439,897 B2
• Filed: 11/04/2008
• Issued: 05/14/2013
• Est. Priority Date: 11/09/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Medingo Ltd. (Roche Holding AG)
• Inventors: Yodfat, Ofer, Shapira, Gali
• Primary Examiner(s): Lucchesi, Nicholas
• Assistant Examiner(s): CHANDER, DIVA KAKAR
• Application Number:
  US12/742,173
• Publication Number:
  US 20100256458A1
• Time in Patent Office: 1,652 Days
• Field of Search: 604 65- 66, 604/504, 604/890.1, 604/891.1
• US Class Current: 604/891.1
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/60 relating to nutrition control, e.g. diets
• CPC Class Codes: G16H 40/60 for the operation of medical equipment or devices
• CPC Class Codes: G16H 40/63 for local operation

Abstract

Methods, systems and devices for assessing residual insulin time of a patient are provided. In one embodiment, the method and the device can be implemented by receiving a confirmation that an insulin dose has been administered to the patient; repetitively receiving a value corresponding to the patient'"'"'s blood glucose level; identifying at least two consecutively received values based on a predetermined criteria; and, selecting the residual insulin time corresponding to a time period between the confirmation that the insulin dose has been administered and a time corresponding to the identification of the at least two consecutively received values.

Claims

1. A method for assessing a residual insulin time of a patient comprising:

receiving a confirmation that an insulin dose has been administered to a the patient, the insulin dose corresponding to an amount of carbohydrates consumed by the patient;

repetitively receiving a value corresponding to the patient'"'"'s blood glucose level;

identifying at least two consecutively received values based on a predetermined criteria; and

assessing a residual insulin time corresponding to a time period between receipt of the confirmation and the identification of the at least two consecutively received values.

2. The method of claim 1, wherein the predetermined criteria is based on a target blood glucose range.

3. The method of claim 2, wherein the two consecutive values are identified only if both consecutive values are within the target blood glucose range.

4. The method of claim 1, wherein the predetermined criteria is based on an initial blood glucose level measured prior to the administration of the insulin dose.

5. The method of claim 1, wherein the predetermined criteria is based on a difference between the at least two consecutively received values.

6. The method of claim 5, wherein the difference is less than 20 mg/dL.

7. The method of claim 1, wherein the insulin dose is administered to the patient subsequently to a confirmation that the patient'"'"'s blood glucose level is within a target blood glucose range.

8. The method of claim 1, wherein the time corresponding to the identification of the at least two consecutively received values is the time when the first of the two identified values was received.

9. The method of claim 1, further comprising advising the patient to bring the patient'"'"'s blood glucose level within a target blood glucose range prior to consuming the carbohydrates.

10. The method of claim 1, further comprising advising the patient to abstain from food for an abstention period of time prior to consuming the carbohydrates and administering the insulin dose.

11. The method of claim 1, wherein the value corresponding to the patient'"'"'s blood glucose level is repetitively received with a predetermined frequency.

12. The method of claim 1, wherein the predetermined criteria is based on a third consecutively received value corresponding to the patient'"'"'s blood glucose level.

13. The method of claim 12, wherein the at least two consecutively received values are identified if the difference between the third consecutive value and the first consecutive value is less than a predefined threshold.

14. The method of claim 1, further comprising initiating an administration of a correction bolus if the two identified consecutively received values are above the target blood glucose range.

15. The method of claim 14, wherein the initiation of the administration of the correction bolus is performed by notifying the patient.

16. The method of claim 14, wherein the initiation of the administration of the correction bolus is performed by activating a pump.

17. The method of claim 1, further comprising advising the patient to assess a carbohydrate-to-insulin ratio (CIR) value if the deviation between one of the at least two consecutively received values and the patient'"'"'s blood glucose level measured prior to the insulin administration exceeds a predefined threshold.

18. The method of claim 1, further comprising advising the patient to consume more carbohydrates if the two identified consecutively received values are below a target blood glucose range.

19. The method of claim 1, wherein the patient'"'"'s blood glucose level is received from a continuous glucose monitor (CGM).

20. A medical device comprising:

a tangible machine-readable storage medium embodying instructions that when performed by one or more processors result in operations comprising;

receiving a confirmation that an insulin dose has been administered to the patient, the insulin dose corresponding to an amount of carbohydrates consumed by the patient;

repetitively receiving a value corresponding to the patient'"'"'s blood glucose level;

identifying at least two consecutively received values based on a predetermined criteria; and

assessing a residual insulin time corresponding to a time period between receipt of the confirmation and the identification of the at least two consecutively received values.

21. The device of claim 20, wherein the predetermined criteria is based on a difference between the at least two consecutively received values.

22. A medical device comprising:

a continuous glucose monitor (CGM); and

a tangible machine-readable storage medium embodying instructions that when performed by one or more processors result in operations comprising;

receiving a confirmation that an insulin dose has been administered to the patient, the insulin dose corresponding to an amount of carbohydrates consumed by the patient;

repetitively receiving a value corresponding to the patient'"'"'s blood glucose level from the continuous glucose monitor (CGM);

identifying at least two consecutively received values based on a predetermined criteria; and

assessing a residual insulin time corresponding to a time period between receipt of the confirmation and the identification of the at least two consecutively received values.