Intraocular implants and related kits and methods

• US 8,439,972 B2
• Filed: 09/26/2011
• Issued: 05/14/2013
• Est. Priority Date: 02/05/2010
• Status: Active Grant

• Current Assignee: Sight Sciences, Inc.
• Original Assignee: Sight Sciences, Inc.
• Inventors: Badawi, Paul, Badawi, David Y.
• Primary Examiner(s): Matthews, William H
• Application Number:
  US13/245,811
• Publication Number:
  US 20120059461A1
• Time in Patent Office: 596 Days
• Field of Search: 623/4.1, 623/1.22, 623/23.69, 604/8
• US Class Current: 623/4.1
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/14 Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
• CPC Class Codes: A61F 2/15 Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2002/0081 directly machined on the prosthetic surface, e.g. holes, grooves A61F2/30771 takes precedence
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm'"'"'s canal and that may restore or maintain at least partial patency of the canal without substantially interfering with transmural or transluminal fluid flow across the canal. The devices utilize the natural drainage process of the eye and may be implanted with minimal trauma to the eye. Kits may include a support and an introducer for implanting the support within Schlemm'"'"'s canal. Methods may include implanting a support within Schlemm'"'"'s canal, where the support is capable of restoring or maintaining at least partial patency of the canal without substantial interference with transmural or transluminal fluid flow across the canal.

Claims

1. A device for reducing intraocular pressure comprising:

a helical support body implantable within at least a portion of Schlemm'"'"'s canal, the helical support body comprising a double helix having a length, a first elongated edge, a second elongated edge, and a central longitudinal axis,

wherein the first and second elongated edges of the double helix are twisted along and about the central longitudinal axis, and comprise a plurality of struts extending therebetween in a direction substantially normal to the central longitudinal axis, and wherein the plurality of struts define a plurality of fenestrations spaced along at least a portion of the length of the helical support body.

2. The device of claim 1, wherein the first and second elongated edges are configured to contact an interior surface of Schlemm'"'"'s canal continuously along the length of the helical support body.

3. The device of claim 1, wherein the first and second elongated edges are configured to contact an interior surface of Schlemm'"'"'s canal at two points at any location along the length of the helical support body.

4. The device of claim 1, wherein one of the proximal and distal ends of the helical support body is blunt, rounded, or elliptical.

5. The device of claim 1, wherein the helical support body is curved.

6. The device of claim 5, wherein the helical support body has a radius of curvature that approximates the curvature of Schlemm'"'"'s canal.

7. The device of claim 6, wherein the helical support body has a radius of curvature of about 2 millimeters to about 23 millimeters.

8. The device of claim 1, wherein the helical support body comprises titanium, stainless steel, or a shape memory alloy.

9. The device of claim 8, wherein the shape memory alloy comprises a nickel titanium alloy.

10. The device of claim 1, wherein the fenestrations are rectangular.