Sustained release intraocular implants and related methods
First Claim
1. A method of treating an ocular condition of a patient, comprising the step of placing an intraocular implant in an eye of the patient to provide a therapeutically effective amount of a steroid to the patient for about one year, wherein said implant comprises a polymeric outer layer covering a core containing a steroid, the polymeric outer layer including a plurality of holes sized to permit the steroid to pass from the implant to an external environment at a rate of less than 2 μ
- g/day for about one year after the implant is placed in an eye of a patient, wherein each of the holes has a diameter of at least about 250 μ
m and less than about 500 μ
m.
1 Assignment
0 Petitions
Accused Products
Abstract
Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.
224 Citations
7 Claims
-
1. A method of treating an ocular condition of a patient, comprising the step of placing an intraocular implant in an eye of the patient to provide a therapeutically effective amount of a steroid to the patient for about one year, wherein said implant comprises a polymeric outer layer covering a core containing a steroid, the polymeric outer layer including a plurality of holes sized to permit the steroid to pass from the implant to an external environment at a rate of less than 2 μ
- g/day for about one year after the implant is placed in an eye of a patient, wherein each of the holes has a diameter of at least about 250 μ
m and less than about 500 μ
m. - View Dependent Claims (2, 3, 4, 5, 6, 7)
- g/day for about one year after the implant is placed in an eye of a patient, wherein each of the holes has a diameter of at least about 250 μ
Specification