Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
First Claim
1. A method of inhibiting or reversing scar formation in a subject in need thereof comprising, administering to the subject a composition comprising:
- pulverized or ground amniotic membrane preparation prepared from placenta that is frozen or previously frozen,wherein scar formation is inhibited or reversed.
5 Assignments
0 Petitions
Accused Products
Abstract
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
106 Citations
16 Claims
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1. A method of inhibiting or reversing scar formation in a subject in need thereof comprising, administering to the subject a composition comprising:
pulverized or ground amniotic membrane preparation prepared from placenta that is frozen or previously frozen, wherein scar formation is inhibited or reversed. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
Specification