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System and method for estimating physiological parameters by deconvolving artifacts

  • US 8,442,608 B2
  • Filed: 12/24/2008
  • Issued: 05/14/2013
  • Est. Priority Date: 12/28/2007
  • Status: Active Grant
First Claim
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1. A method for non-invasively estimating a physiological parameter comprising:

  • detecting light over a period of time from a plurality of light sources comprising at least three light sources;

    generating respective distributions for the detected light of each of the plurality of light sources for the period of time;

    deconvolving the distribution for the detected light of one of the plurality of light sources from each of the other distributions for the detected light from the other plurality of light sources to produce clean distributions for the period of time; and

    estimating a physiological parameter based at least in part upon the clean distributions;

    wherein deconvolving the distribution for the detected light of one of the plurality of light sources comprises using a least squares algorithm, wherein the least squares algorithm comprises;

    formulating a toeplitz matrix A associated with f; and

    finding a vector g with nonnegative elements such that (Ag-f)T(Ag-f) is minimized, wherein g and f are bi-infinite sequences.

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