System and method for estimating physiological parameters by deconvolving artifacts
First Claim
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1. A method for non-invasively estimating a physiological parameter comprising:
- detecting light over a period of time from a plurality of light sources comprising at least three light sources;
generating respective distributions for the detected light of each of the plurality of light sources for the period of time;
deconvolving the distribution for the detected light of one of the plurality of light sources from each of the other distributions for the detected light from the other plurality of light sources to produce clean distributions for the period of time; and
estimating a physiological parameter based at least in part upon the clean distributions;
wherein deconvolving the distribution for the detected light of one of the plurality of light sources comprises using a least squares algorithm, wherein the least squares algorithm comprises;
formulating a toeplitz matrix A associated with f; and
finding a vector g with nonnegative elements such that (Ag-f)T(Ag-f) is minimized, wherein g and f are bi-infinite sequences.
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Abstract
There is disclosed a system and methods to estimate physiological parameters. In accordance with embodiments a method is disclosed which includes generating distribution data for a plurality of signals. The method may also include deconvolving one of the plurality of signals from the other plurality of signals to produce clean signals. The clean signals may then be used to calculate physiological parameters.
884 Citations
22 Claims
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1. A method for non-invasively estimating a physiological parameter comprising:
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detecting light over a period of time from a plurality of light sources comprising at least three light sources; generating respective distributions for the detected light of each of the plurality of light sources for the period of time; deconvolving the distribution for the detected light of one of the plurality of light sources from each of the other distributions for the detected light from the other plurality of light sources to produce clean distributions for the period of time; and estimating a physiological parameter based at least in part upon the clean distributions; wherein deconvolving the distribution for the detected light of one of the plurality of light sources comprises using a least squares algorithm, wherein the least squares algorithm comprises; formulating a toeplitz matrix A associated with f; and finding a vector g with nonnegative elements such that (Ag-f)T(Ag-f) is minimized, wherein g and f are bi-infinite sequences. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system for estimating a physiological parameter comprising:
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a sensor comprising; a plurality of light sources; and a detector configured to generate signals based on detected light from the plurality of light sources over a period of time; and a monitor coupled to the sensor configured to; generate distribution data based on the detected light for the period of time for each of the plurality of light sources; and deconvolve distribution data for the period of time of one of the plurality of light sources from the distribution data of each of the other plurality of light sources for the period of time, to produce clean distributions; wherein deconvolving the distribution data comprises the monitor using a least squares algorithm, wherein the least squares algorithm comprises; formulating a toeplitz matrix A associated with f; and finding a vector g with nonnegative elements such that (Ag-f)T(Ag-f) is minimized, wherein q and f are bi-infinite sequences. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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21. A method for non-invasively estimating a physiological parameter comprising:
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detecting light over a period of time from a plurality of light sources comprising at least three light sources; generating respective distributions for the detected light of each of the plurality of light sources for the period of time; calibrating functions representative of a distribution of a noise signal, wherein calibrating functions representative of the distribution of the noise signal comprises; collecting a first set of data for each of the plurality light sources; collecting a second set of data for each of the plurality of light sources; and parameterizing the functions representative of the distribution of the noise signal, wherein parameterizing the functions comprises finding a parameter to produce approximately equal distributions of the first and second sets of data; deconvolving the distribution for the detected light of one of the plurality of light sources from each of the other distributions for the detected light from the other plurality of light sources to produce clean distributions for the period of time; and estimating a physiological parameter based at least in part upon the clean distributions.
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22. A system for estimating a physiological parameter comprising:
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a sensor comprising; a plurality of light sources; and a detector configured to generate signals based on detected light from the plurality of light sources over a period of time; and a monitor coupled to the sensor configured to; generate distribution data based on the detected light for the period of time for each of the plurality of light sources; calibrate functions representative of a distribution of a noise signal, wherein calibrating functions representative of the distribution of the noise signal comprises; collecting a first set of data for each of the plurality light sources; collecting a second set of data for each of the plurality of light sources; and parameterizing the functions representative of the distribution of the noise signal, wherein parameterizing the functions comprises finding a parameter to produce approximately equal distributions of the first and second sets of data; and deconvolve distribution data for the period of time of one of the plurality of light sources from the distribution data of each of the other plurality of light sources for the period of time, to produce clean distributions.
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Specification