Methods for selectively heating tissue

• US 8,444,635 B2
• Filed: 11/16/2009
• Issued: 05/21/2013
• Est. Priority Date: 11/19/2008
• Status: Active Grant

• Current Assignee: IKOMED Technologies Inc.
• Original Assignee: Daniel Gelbart, Samuel Victor Lichtenstein
• Inventors: Lichtenstein, Samuel Victor, Gelbart, Daniel
• Primary Examiner(s): Dvorak, Linda
• Assistant Examiner(s): Ram, Jocelyn D
• Application Number:
  US12/590,807
• Publication Number:
  US 20100125271A1
• Time in Patent Office: 1,282 Days
• Field of Search: 606/17, 606/18, 606/33, 606/34, 607/90, 607/91, 607/94, 607/100, 607/101, 607/142, 607/148
• US Class Current: 606/33
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 34/30 Surgical robots

Abstract

The invention can selectively heat a diseased area or undesired tissue in the body while minimizing heating to the healthy area and surrounding tissue. This is done by exposing the undesired tissue to a scanning focused microwave beam arriving from different directions, all directions passing through the undesired tissue. The invention is particularly useful for heating tissues in which the undesired tissue has reduced blood flow. The undesired area will heat up rapidly while the healthy tissue will be cooled by the blood flow. This is particularly effective for treating emphysema because of the low mass of the lungs and the high blood flow.

Claims

1. A method for treating emphysema, the method comprising of:

providing a source of microwave radiation,

focusing the microwave radiation to form a focused spot,

aiming the focused spot onto a lung of a patient affected by emphysema, the lung comprising healthy and non-healthy areas of lung tissue, the healthy areas having higher rates of blood flow than the non-healthy areas,

moving the source of microwave radiation along a path around the body of the patient while the patient is breathing, while aiming the focused spot onto the lung,

continuing to aim the focused spot onto the lung until at least a portion of the non-healthy areas reaches at least a first temperature while allowing the higher rates of blood flow in the healthy areas to carry away heat from the healthy areas and thereby prevent the healthy areas from exceeding a second temperature, lower than the first temperature,

wherein the first temperature is at least 50 degrees Celsius and the second temperature is no more than 45 degrees Celsius.

2. The method as in claim 1 wherein the focused spot is larger than some of the non-healthy areas.

3. The method as in claim 1 further comprising temporarily collapsing the lung.

4. The method as in claim 1 wherein the microwave radiation has a frequency of approximately 2.45 GHz.

5. The method as in claim 1 wherein the power of the microwave radiation is lower than the power necessary for ablation of the non-healthy areas, and wherein the method further comprises measuring reflection or absorption of the microwave radiation for imaging.

6. The method as in claim 1 wherein the first temperature is at least 60 degrees C.

7. The method as in claim 1 further comprising administering chilled air to the patient for breathing while aiming the focused spot onto the lung.

8. The method as in claim 1 further comprising coating at least part of the skin of the patient with an impedance matching coating for reducing reflection of microwave energy.

9. The method as in claim 1 wherein the path of the source of microwave radiation allows the focused spot to be continuously aimed onto the lung without the microwave radiation passing through sensitive organs of the patient.

10. The method as in claim 9 wherein the sensitive organs include the head, the heart, and the spine.

11. The method as in claim 1 wherein the microwave radiation has a frequency of approximately 915 Mhz.

12. The method as in claim 1 further comprising using an apodizing plate to shape the microwave radiation.