Compositions of R(+) and S(−) pramipexole and methods of using the same
First Claim
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1. A method of treating and delaying the progression of Parkinson'"'"'s disease or the symptoms thereof comprising administering to a subject in need thereof 100 milligrams to about 3,000 milligrams of R(+) pramipexole in combination with about 0.125 mg to about 1.5 milligrams of S(−
- ) pramipexole, wherein said Parkinson'"'"'s disease or the symptoms thereof is treated and the progression is delayed.
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Abstract
Compositions of predetermined amounts of R(+) pramipexole and S(−) pramipexole and methods of using the same, including for the treatment and prevention of Parkinson'"'"'s disease, are provided.
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Citations
57 Claims
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1. A method of treating and delaying the progression of Parkinson'"'"'s disease or the symptoms thereof comprising administering to a subject in need thereof 100 milligrams to about 3,000 milligrams of R(+) pramipexole in combination with about 0.125 mg to about 1.5 milligrams of S(−
- ) pramipexole, wherein said Parkinson'"'"'s disease or the symptoms thereof is treated and the progression is delayed.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of treating Parkinson'"'"'s disease or the symptoms thereof comprising administering to a subject in need thereof 100 milligrams to about 3,000 milligrams of R(+) pramipexole in combination with about 0.125 mg to about 1.5 milligrams of S(−
- ) pramipexole, wherein said Parkinson'"'"'s disease or the symptoms thereof is treated.
- View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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39. A method of delaying the progression of Parkinson'"'"'s disease or the symptoms thereof comprising administering to a subject in need thereof 100 milligrams to about 3,000 milligrams of R(+) pramipexole in combination with about 0.125 mg to about 1.5 milligrams of S(−
- ) pramipexole, wherein the progression of Parkinson'"'"'s disease or symptoms thereof is delayed.
- View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57)
Specification