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Dendrimer conjugates

  • US 8,445,528 B2
  • Filed: 07/12/2012
  • Issued: 05/21/2013
  • Est. Priority Date: 03/12/2008
  • Status: Active Grant
First Claim
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1. A dendrimer conjugate comprising a linker,wherein said linker is selected from the group consisting of an elimination linker, a cyclization linker, a glucoronidase sensitive linker, a branched self-elimination linker, a heteroaromatic nitrogen containing compound linker, and a hypoxia induced linker,wherein said linker is conjugated to a G5 PAMAM dendrimer and at least one ligand selected from the group consisting of a therapeutic agent, an imaging agent, and a targeting agent.

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