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Device and implantation system for electrical stimulation of biological systems

  • US 8,447,404 B2
  • Filed: 03/04/2011
  • Issued: 05/21/2013
  • Est. Priority Date: 03/05/2010
  • Status: Active Grant
First Claim
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1. A system for increasing pressure of a patient'"'"'s lower esophageal sphincter (LES), comprising:

  • at least one electrode contacting the LES;

    a waveform generator coupled to the electrodes; and

    a controller configured to electrically stimulate the LES to increase the pressure of the LES, control the waveform generator to stimulate the LES based on a predetermined trigger of at least one of time of day and a supine position of the patient, and maintain an average pressure of the LES above a pressure level which reduces at least one of a frequency of occurrence or an intensity of diurnal GERD symptoms in the patient both during and after stimulation by controlling the waveform generator to repeatedly;

    a) generate and apply an electrical pulse train to the LES through the electrodes for a stimulation period, and b) terminate the electrical pulse train for a rest period.

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