Cellular labeling for nuclear magnetic resonance techniques
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1. A method for labeling a cell, the method comprising contacting the cell ex vivo with a fluorocarbon imaging reagent under conditions such that the fluorocarbon imaging reagent becomes associated with the cell wherein the fluorocarbon imaging reagent is internalized into the cell.
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Abstract
This disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The disclosure additionally provides methods for using the imaging reagents in a variety of clinical procedures.
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19 Claims
- 1. A method for labeling a cell, the method comprising contacting the cell ex vivo with a fluorocarbon imaging reagent under conditions such that the fluorocarbon imaging reagent becomes associated with the cell wherein the fluorocarbon imaging reagent is internalized into the cell.
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