Non-invasive ultrasonic body contouring

• US 8,454,540 B2
• Filed: 12/17/2010
• Issued: 06/04/2013
• Est. Priority Date: 10/29/2001
• Status: Expired due to Fees

• Current Assignee: Ultrashape Ltd.
• Original Assignee: Ultrashape Ltd.
• Inventors: Eshel, Yoram, Vitsnudel, Ilia
• Primary Examiner(s): Jung, Unsu
• Assistant Examiner(s): Lamprecht, Joel
• Application Number:
  US12/971,603
• Publication Number:
  US 20110087099A1
• Time in Patent Office: 900 Days
• Field of Search: 600/407, 600/437, 601/1, 601/2, 601/3
• US Class Current: 601/1
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2034/2055 Optical tracking systems
• CPC Class Codes: A61B 2034/2065 Tracking using image or pattern recognition
• CPC Class Codes: A61B 2034/2072 Reference field transducer attached to an instrument or patient
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3937 Visible markers
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 34/25 User interfaces for surgical systems
• CPC Class Codes: A61B 90/361 Image-producing devices, e.g. surgical cameras
• CPC Class Codes: A61N 2007/0008 Destruction of fat cells
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092

Abstract

An apparatus for lysing adipose tissue, the apparatus comprising a power source and a modulator assembly configured to supply modulated electrical power; an ultrasonic therapeutic transducer connected to the power source and modulator assembly and configured to convert the modulated electrical power to ultrasonic energy directed at a target volume in a region of a body containing adipose and non-adipose tissue, so as to selective generally lyse the adipose tissue and generally not lyse the non-adipose tissues; an ultrasonic imaging sub-system configured to identify changes in the target volume resulting from the ultrasonic energy; and a lipolysis control computer configured to control the power source and modulator assembly based on the changes identified by the ultrasonic imaging sub-system.

Claims

1. An apparatus for lysing adipose tissue, the apparatus comprising:

a power source and modulator assembly configured to supply modulated electrical power;

an ultrasonic therapeutic transducer connected to said power source and modulator assembly and configured to convert the modulated electrical power to therapeutic ultrasonic energy directed at a target volume in a region of a body containing adipose and non-adipose tissue, so as to selectively lyse adipose tissue and not lyse non-adipose tissue which receives the therapeutic ultrasonic energy;

an ultrasonic imaging sub-system configured to identify changes in the target volume resulting from the therapeutic ultrasonic energy; and

a lipolysis control computer configured to control said power source and modulator assembly based on the changes identified by said ultrasonic imaging sub-system.

2. The apparatus according to claim 1, wherein said ultrasonic imaging sub-system comprises an ultrasonic imaging transducer and an ultrasonic reflection analyzer.

3. The apparatus according to claim 2, wherein the changes identified by said ultrasonic imaging sub-system comprise cavitation in the target volume.

4. The apparatus according to claim 2, wherein the changes identified by said ultrasonic imaging sub-system comprise lysis of adipose tissue in the target volume.

5. The apparatus according to claim 1, wherein said ultrasonic therapeutic transducer comprises a director configured to vary a focus of the therapeutic ultrasonic energy directed towards the target volume.

6. The apparatus according to claim 5, wherein the varying of the focus comprises changing a volume of said target volume.

7. The apparatus according to claim 5, wherein the varying of the focus comprises changing a distance of said target volume from said ultrasonic therapeutic transducer.

8. A method for selectively lysing adipose tissue, the method comprising:

generating a time-varying electrical signal having a time-separated series at a duty cycle of between 1;

2 to 1;

50, of high amplitude portions each corresponding to a cavitation period and each comprising multiple pulses;

converting the electrical signal to therapeutic ultrasonic energy; and

directing the therapeutic ultrasonic energy towards a target volume in a region of a body containing adipose and non-adipose tissue, thereby inducing selective cavitation in adipose tissue while not lysing non-adipose tissue which receives the therapeutic ultrasonic energy.

9. The method according to claim 8, wherein the time-separated series of high amplitude portions comprises:

one or more initial portions having amplitude above a cavitation initiation threshold; and

later portions having an amplitude above a cavitation maintenance threshold.

10. The method according to claim 9, wherein the time-separated series of high amplitude portions comprises between 25-500 high amplitude portions.

11. The method according to claim 8, wherein the therapeutic ultrasonic energy has a frequency in the range of 150-1000 KHz.

12. An automatically-positionable adipose tissue lysis apparatus, comprising:

a therapeutic ultrasonic transducer secured to a three-dimensional positioning assembly, said therapeutic ultrasonic transducer being configured to direct therapeutic ultrasonic energy at a target volume in a region of a body containing adipose and non-adipose tissue, so as to selectively lyse adipose tissue and not lyse non-adipose tissue which receives the therapeutic ultrasonic energy;

a lipolysis control computer having a video camera connected thereto, said video camera being configured to externally image a portion of the body, and said lipolysis control computer being configured to detect indications on the imaged portion of the body; and

a positioning control unit configured to control said three-dimensional positioning assembly so as to automatically position said ultrasonic transducer based on the detected indications.

13. The apparatus according to claim 12, further comprising a lipolysis control computer connected to said positioning control unit and configured to control the directing of the therapeutic ultrasonic energy from said therapeutic ultrasonic transducer based on the detected indications.

14. The apparatus according to claim 13, further comprising an ultrasonic imaging sub-system connected to said lipolysis control computer and configured to identify changes in the target volume resulting from the therapeutic ultrasonic energy, wherein said lipolysis control computer is further configured to control the directing of the therapeutic ultrasonic energy from said therapeutic ultrasonic transducer based on the identified changes.

15. The apparatus according to claim 14, wherein the changes identified by said ultrasonic imaging sub-system comprise cavitation in the target volume.

16. The apparatus according to claim 14, wherein the changes identified by said ultrasonic imaging sub-system comprise lysis of adipose tissue in the target volume.

17. The apparatus according to claim 13, further comprising an ultrasonic imaging sub-system connected to said lipolysis control computer and configured to detect thicknesses of tissue layers in the region of the body, wherein said lipolysis control computer is further configured to control the directing of the therapeutic ultrasonic energy from said ultrasonic transducer based on the detected thicknesses.

18. The apparatus according to claim 17, wherein said lipolysis control computer is further configured to control a focus of said therapeutic ultrasonic transducer, so as to vary a distance of said target volume from said therapeutic ultrasonic transducer.