Device and method for controlling injection of liquid embolic composition

• US 8,454,649 B2
• Filed: 06/02/2011
• Issued: 06/04/2013
• Est. Priority Date: 10/17/1997
• Status: Expired due to Fees

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Cragg, Andrew H., Walker, Blair D., Perl, John II, Jones, Michael, Greene, George Robert, Wallace, George, Greff, Richard J.
• Primary Examiner(s): BOUCHELLE, LAURA A
• Application Number:
  US13/152,208
• Publication Number:
  US 20110264073A1
• Time in Patent Office: 733 Days
• Field of Search: 604/508, 604/523, 604/165, 604/104, 606/108, 606/191, 606/200, 623/1.1, 623/1.21, 623/0.13, 623/1.39, 623/1.4
• US Class Current: 606/200
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 17/12195 comprising a curable material
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: A61B 2017/00876 magnetic
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12059 Joint of soluble material
• CPC Class Codes: A61B 2017/12063 electrolytically detachable
• CPC Class Codes: A61M 2025/0036 with more than four lumina
• CPC Class Codes: A61M 2025/004 characterized by lumina being arranged circumferentially
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 25/0028 characterized by features relating to at least one lumen located at the proximal part of the catheter, e.g. alterations in lumen shape or valves catheter hubs A61M25/0097
• CPC Class Codes: A61M 25/0097 : characterised by the hub connectors A61M39/10

Abstract

A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

Claims

1. A liquid embolic delivery system comprising:

a catheter having a lumen for delivery of a liquid embolic composition including a solvent to a cavity;

a containment member positioned at a distal end of the catheter, the containment member shaped to trap the liquid embolic composition delivered through the lumen of the catheter, the containment member being permeable to the solvent of the liquid embolic composition to allow the solvent to dissipate from the liquid embolic composition; and

a detachment mechanism for completely detaching the containment member from the catheter after solidification of the liquid embolic composition to allow separation of the catheter from a mass of solidified embolic composition.

2. The liquid embolic delivery system according to claim 1, wherein the containment member is a flexible sack which fills with the liquid embolic composition.

3. The liquid embolic delivery system according to claim 2, wherein the flexible sack is positioned over a distal outlet of the lumen with a neck of the sack connected to the distal end of the catheter around an opening of the catheter lumen, the detachment mechanism detaching the flexible sack neck from the distal end of the catheter.

4. The liquid embolic delivery system according to claim 2, wherein the flexible sack is formed of a mesh material which allows solvent to pass through the sack, the mesh material containing the liquid embolic composition which has solidified.

5. The liquid embolic delivery system according to claim 2, wherein the flexible sack is formed as a resilient balloon over the distal end of the catheter.

6. The liquid embolic delivery system according to claim 1, wherein the containment member is a nidus extending from the distal end of the catheter and positioned to trap the liquid embolic composition as the liquid embolic composition solidifies.

7. The liquid embolic delivery system according to claim 6, wherein the nidus is formed from a wire which is delivered through the catheter lumen and forms a coil upon exiting the distal end of the lumen.

8. The liquid embolic delivery system according to claim 6, wherein the nidus is in the form of a wire brush.

9. The liquid embolic delivery system according to claim 6, wherein the nidus is in the form of a swab.

10. The liquid embolic delivery system according to claim 6, wherein the nidus is in the form of a flexible sack.

11. The liquid embolic delivery system according to claim 6, wherein the nidus is formed from a wire which is delivered through the catheter lumen and forms a randomly shaped nest upon exiting the distal end of the lumen.

12. The liquid embolic delivery system according to claim 1, wherein the detachment mechanism includes means for delivering an electrical charge to a point between the containment member and the catheter to detach the containment member from the catheter.

13. The liquid embolic delivery system according to claim 1, wherein the detachment mechanism includes a chemical detachment section between the containment member and the catheter which is dissolved by a chemical agent.

14. A liquid embolic delivery system comprising:

a catheter having a lumen for delivery of a liquid embolic composition to a cavity;

a containment member positioned at a distal end of the catheter, the containment member shaped to trap the liquid embolic composition delivered through the lumen of the catheter; and

a detachment mechanism for completely detaching the containment member from the catheter after solidification of the liquid embolic composition to allow separation of the catheter from a mass of solidified embolic composition, wherein the containment member is a nidus extending from the distal end of the catheter and positioned to trap the liquid embolic composition as the liquid embolic composition solidifies, wherein the nidus is in the form of a sponge.