Systems for forming reagent with reduced background current

• US 8,454,806 B2
• Filed: 12/09/2008
• Issued: 06/04/2013
• Est. Priority Date: 12/10/2007
• Status: Active Grant

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Jung, Sung-Kwon, Charlton, Steven C., Huang, Dijia
• Primary Examiner(s): Hendricks, Keith
• Assistant Examiner(s): Friday, Steven A.
• Application Number:
  US12/316,105
• Publication Number:
  US 20090148593A1
• Time in Patent Office: 1,638 Days
• Field of Search: 204/275.1, 204/403.01, 204/411, 204/412, 204/242, 204/403.02, 204/403.03, 204/403.04, 205/701, 205/687, 422/400, 422/401, 422/407
• US Class Current: 204/242
• CPC Class Codes: C12Q 1/001 Enzyme electrodes
• CPC Class Codes: C25D 11/02 Anodisation
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: Y10T 29/49117 Conductor or circuit manufacturing

Abstract

Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current.

Claims

1. A system comprising:

a receptacle including an amount of a test-sensor reagent, the test-sensor reagent including a mediator and an enzyme;

a first electrode and a second electrode for contacting the test-sensor reagent, the first electrode and the second electrode having hollow interior portions, wherein oxidation occurs at at least one of the first electrode or the second electrode to produce a modified test-sensor reagent having a reduced background current, the test-sensor reagent being directed from the receptacle to the first electrode and the second electrode through a tubing; and

a test sensor for receiving the modified test-sensor reagent having a reduced background current, the test sensor including a lid and base, the lid and base assisting in forming a fluid-receiving area that provides a flow path for introducing a fluid sample.

2. The system of claim 1, wherein the first electrode is a counter electrode, the first electrode comprising platinum, carbon, gold, palladium, ruthenium, rhodium or combinations thereof.

3. The system of claim 1, wherein the second electrode is a working electrode, the working electrode comprising platinum, carbon, gold, palladium, ruthenium, rhodium or combinations thereof.

4. The system of claim 1, further comprising a third electrode.

5. The system of claim 4, wherein the third electrode is a reference electrode, the third electrode comprising silver, silver chloride, mercury chloride or combinations thereof.

6. The system of claim 1, further including a valve to assist in controlling the flow of the test-sensor reagent.

7. The system of claim 1, wherein the test-sensor reagent flows through the first electrode prior to flowing through the second electrode.

8. The system of claim 1, wherein the receptacle includes glass.

9. The system of claim 1, wherein the receptacle includes polycarbonate or polystyrene.

10. The system of claim 1, wherein the tubing comprises a clear rigid or semi-rigid plastic material.

11. The system of claim 1, wherein the test sensor is an electrochemical test sensor.

12. The system of claim 1 wherein the test sensor includes two additional electrodes.

13. The system of claim 1, wherein the test sensor is an optical test sensor.