Methods for treating coagulation disorders
First Claim
1. A method for treating Hemophilia A in a patient in need thereof comprising administering to the patient a therapeutically effective amount of a substantially purified population of cultured non-genetically modified amnion-derived epithelial cells, wherein the amnion-derived epithelial cells are made by a method comprising the steps ofa) obtaining a placenta and isolating an amnion from the placenta,b) enzymatically releasing amnion-derived epithelial cells from the amnion,c) collecting the released amnion-derived epithelial cells, andd) culturing the collected amnion-derived epithelial cells of step (c) in basal culture medium that is supplemented with human serum albumin and recombinant human EGF.
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Accused Products
Abstract
The invention is directed to methods for treating coagulation disorders, in particular, hemophilia. Such methods utilize novel compositions including Amnion-derived Multipotent Progenitor cells (herein referred to as AMP cells) alone or in combination with other agents and/or treatment modalities.
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Citations
5 Claims
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1. A method for treating Hemophilia A in a patient in need thereof comprising administering to the patient a therapeutically effective amount of a substantially purified population of cultured non-genetically modified amnion-derived epithelial cells, wherein the amnion-derived epithelial cells are made by a method comprising the steps of
a) obtaining a placenta and isolating an amnion from the placenta, b) enzymatically releasing amnion-derived epithelial cells from the amnion, c) collecting the released amnion-derived epithelial cells, and d) culturing the collected amnion-derived epithelial cells of step (c) in basal culture medium that is supplemented with human serum albumin and recombinant human EGF.
Specification