Apparatus and method for identifying atrial arrhythmia by far-field sensing

• US 8,457,737 B2
• Filed: 09/13/2011
• Issued: 06/04/2013
• Est. Priority Date: 11/21/2001
• Status: Expired due to Term

• Current Assignee: Cameron Incorporated (Schlumberger NV)
• Original Assignee: Cameron Incorporated (Schlumberger NV)
• Inventors: Bardy, Gust H., Rissmann, William J., Ostroff, Alan H., Erlinger, Paul J., Allavatam, Venugopal
• Primary Examiner(s): GETZOW, SCOTT M
• Application Number:
  US13/231,613
• Publication Number:
  US 20110319949A1
• Time in Patent Office: 630 Days
• Field of Search: 607 4- 28
• US Class Current: 607/5
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting
• CPC Class Codes: A61N 1/3931 Protecting, e.g. back-up systems
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

In a subcutaneous implantable cardioverter/defibrillator, cardiac arrhythmias are detected to determine necessary therapeutic action. Cardiac signal information is sensed from far field electrodes implanted in a patient. The sensed cardiac signal information is then amplified and filtered. Parameters such as rate, QRS pulse width, cardiac QRS slew rate, amplitude and stability measures of these parameters from the filtered cardiac signal information are measured, processed and integrated to determine if the cardioverter/defibrillator needs to initiate therapeutic action.

Claims

1. A method of treating a patient with an implanted cardioverter-defibrillator comprising:

the implanted cardioverter-defibrillator capturing far-field cardiac signals from electrodes disposed beneath the skin and outside of a patient'"'"'s ribcage;

the implanted cardioverter-defibrillator identifying the patient'"'"'s P-wave in the far-field cardiac signals;

the implanted cardioverter-defibrillator monitoring the patient'"'"'s P-wave to determine whether the patient'"'"'s P-wave abruptly changes; and

the implanted cardioverter-defibrillator if the patient'"'"'s P-wave abruptly changes, determining that the patient is experiencing atrial fibrillation and withholding cardiac stimulus that would otherwise be delivered to the patient.

2. The method of claim 1, wherein the implanted cardioverter-defibrillator comprises a lead assembly coupled to a canister that houses operational circuitry for the implanted cardioverter-defibrillator wherein the canister and the lead assembly are implanted in the patient beneath the skin and outside of the patient'"'"'s ribcage without accessing the vasculature or heart of the patient.

3. The method of claim 1, further comprising withholding cardiac stimulus that would otherwise be delivered to the patient if it is determined that the patient is experiencing atrial fibrillation.

4. The method of claim 1, wherein the step of monitoring the patient'"'"'s P-wave includes determining whether the patient'"'"'s P-wave disappears and, if so, concluding that the P-wave has abruptly changed.

5. The method of claim 1, further comprising identifying at least one characteristic of the patient'"'"'s P-wave during normal sinus rhythm.

6. The method of claim 5, wherein the at least one characteristics of the patient'"'"'s P-wave includes the morphology of the patient'"'"'s P-wave during normal sinus rhythm, and further wherein an abrupt change is determined by observation of whether a change occurs in the morphology of the patient'"'"'s P-wave.

7. The method of claim 5, wherein the at least one characteristic of the patient'"'"'s P-wave includes the amplitude and timing relationship of the patient'"'"'s P-wave to the patient'"'"'s QRS during normal sinus rhythm, and further wherein an abrupt change is determined by observation of whether a change occurs in the amplitude and timing relationship of the patient'"'"'s P-wave to the patient'"'"'s QRS during an unknown rhythm.

8. The method of claim 5, wherein the at least one characteristic of the patient'"'"'s P-wave includes the frequency content of the patient'"'"'s P-wave during normal sinus rhythm, and further wherein an abrupt change is determined by observation of whether a change occurs in the frequency content of the patient'"'"'s P-wave.

9. The method of claim 5, wherein the at least one characteristic of the patient'"'"'s P-wave includes the timing of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS during normal sinus rhythm, and further wherein an abrupt change is determined by observation of whether a change occurs in the timing of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS.

10. The method of claim 5, wherein the at least one characteristic of the patient'"'"'s P-wave includes polarity of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS during normal sinus rhythm, and further wherein an abrupt change is determined by observation of whether a change occurs in the polarity of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS.

11. An implantable cardioverter defibrillator (ICD) comprising a housing containing operational circuitry that is coupled to a plurality of electrodes for implantation in a patient, wherein the operational circuitry is configured to perform the following method of cardiac signal analysis while implanted in a patient:

capturing far-field cardiac signals from electrodes disposed beneath the skin and outside of a patient'"'"'s ribcage;

identifying the patient'"'"'s P-wave in the far-field cardiac signals;

monitoring the patient'"'"'s P-wave to determine whether the patient'"'"'s P-wave abruptly changes; and

if the patient'"'"'s P-wave abruptly changes, determining that the patient is experiencing atrial fibrillation and withholding cardiac stimulus that would otherwise be delivered to the patient.

12. The ICD of claim 11, wherein the operational circuitry is further configured to withhold cardiac stimulus that would otherwise be delivered to the patient if it is determined that the patient is experiencing atrial fibrillation.

13. The ICD of claim 11, wherein the operational circuitry is further configured such that the step of monitoring the patient'"'"'s P-wave includes determining whether the patient'"'"'s P-wave disappears and, if so, concluding that the P-wave has abruptly changed.

14. The ICD of claim 11, wherein the operational circuitry is further configured such that the method also includes identifying at least one characteristic of the patient'"'"'s P-wave during normal sinus rhythm.

15. The ICD of claim 14, wherein the operational circuitry is further configured such that:

the at least one characteristic of the patient'"'"'s P-wave includes the morphology of the patient'"'"'s P-wave during normal sinus rhythm; and

an abrupt change is determined by observation of whether a change occurs in the morphology of the patient'"'"'s P-wave.

16. The ICD of claim 14, wherein the operational circuitry is further configured such that:

the at least one characteristic of the patient'"'"'s P-wave includes the amplitude and timing relationship of the patient'"'"'s P-wave to the patient'"'"'s QRS during normal sinus rhythm; and

wherein an abrupt change is determined by observation of whether a change occurs in the amplitude and timing relationship of the patient'"'"'s P-wave to the patient'"'"'s QRS.

17. The ICD of claim 14, wherein the operational circuitry is further configured such that:

the at least one characteristic of the patient'"'"'s P-wave includes the frequency content of the patient'"'"'s P-wave during normal sinus rhythm; and

an abrupt change is determined by observation of whether a change occurs in the frequency content of the patient'"'"'s P-wave.

18. The ICD of claim 14, wherein the operational circuitry is further configured such that:

the at least one characteristic of the patient'"'"'s P-wave includes the timing of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS during normal sinus rhythm; and

an abrupt change is determined by observation of whether a change occurs in the timing of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS.

19. The ICD of claim 14, wherein the operational circuitry is further configured such that:

the at least one characteristic of the patient'"'"'s P-wave includes polarity of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS during normal sinus rhythm; and

an abrupt change is determined by observation of whether a change occurs in the polarity of the patient'"'"'s P-wave in relation to the patient'"'"'s QRS.

20. A method of treating a patient with a defibrillator comprising a housing containing operational circuitry and a lead having electrodes thereon coupled to the housing comprising implanting the housing beneath the skin and outside of the patients ribcage and implanting the lead beneath the skin and outside of the patients ribcage such without accessing the vasculature or heart of the patient;

wherein the defibrillator'"'"'s operational circuitry is configured, once implanted, to perform a method of cardiac signal analysis comprising;

capturing far-field cardiac signals from at least one electrode of the lead;

identifying the patient'"'"'s P-wave in the far-field cardiac signals;

monitoring the patient'"'"'s P-wave to determine whether the patient'"'"'s P-wave abruptly changes; and

if the patient'"'"'s P-wave abruptly changes, determining that the patient is experiencing atrial fibrillation and withholding cardiac stimulus that would otherwise be delivered to the patient.