Neurostimulation with signal duration determined by a cardiac cycle
First Claim
1. A method of providing an electrical signal to a cranial nerve of a patient for treating a medical condition, comprising:
- a) determining a cardiac cycle duration of at least a portion of a cardiac cycle;
b) determining a stimulation duration which is based on a predetermined fraction of the determined cardiac cycle duration, wherein the predetermined fraction is less than one;
c) generating an electrical signal based on the stimulation duration;
d) applying the electrical signal to the cranial nerve for the stimulation duration,wherein the electrical signal is operative to deliver an electrical signal stimulation to a patient'"'"'s brain via the cranial nerve; and
e) repeating a-d to automatically adjust the stimulation duration based on changes in the at least a portion of the cardiac cycle.
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Accused Products
Abstract
We disclose a method of providing an electrical signal to a cranial nerve of a patient for treating a medical condition, comprising providing an electrical signal generator, coupling at least a first electrode to a cranial nerve of the patient and to the electrical signal generator, generating an electrical signal with the electrical signal generator, and applying the electrical signal to the cranial nerve, using the at least a first electrode, for a duration less than a cardiac period of the patient and during the cardiac period of the patient. We also disclose an implantable medical device capable of implementing the method.
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Citations
19 Claims
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1. A method of providing an electrical signal to a cranial nerve of a patient for treating a medical condition, comprising:
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a) determining a cardiac cycle duration of at least a portion of a cardiac cycle; b) determining a stimulation duration which is based on a predetermined fraction of the determined cardiac cycle duration, wherein the predetermined fraction is less than one; c) generating an electrical signal based on the stimulation duration; d) applying the electrical signal to the cranial nerve for the stimulation duration, wherein the electrical signal is operative to deliver an electrical signal stimulation to a patient'"'"'s brain via the cranial nerve; and e) repeating a-d to automatically adjust the stimulation duration based on changes in the at least a portion of the cardiac cycle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. An implantable medical device (IMD), comprising:
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an electrical signal generator; and a cardiac cycle determination module configured to determine a cardiac cycle duration of at least a portion of a cardiac cycle of a patient;
wherein;the electrical signal generator is configured to provide an electrical signal to a target tissue via a first electrode for a stimulation duration, wherein the stimulation duration is based on a predetermined fraction of a determined cardiac cycle duration, wherein the predetermined fraction is less than one, the stimulation duration being automatically adjusted in response to changes in the at least a portion of the cardiac cycle of the patient; and wherein the electrical signal is operative to deliver an electrical signal stimulation to a patient'"'"'s brain. - View Dependent Claims (15, 16)
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17. An implantable medical device, comprising:
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an electrical signal generator; and a cardiac cycle determination module adapted to determine a cardiac cycle duration of a patient; and wherein the electrical signal generator is configured to generate and to deliver at least one electrical signal to a target tissue via a first electrode; and wherein a stimulation duration of a delivery of the at least one electrical signal is a predetermined fraction of a determined cardiac cycle duration, wherein the predetermined fraction is less than one, the stimulation duration being automatically adjusted in response to changes in a heart parameter of the patient. - View Dependent Claims (18, 19)
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Specification