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System and method for promoting diuresis and natriuresis by the application of electric fields to the kidney

  • US 8,457,761 B2
  • Filed: 01/07/2010
  • Issued: 06/04/2013
  • Est. Priority Date: 01/14/2009
  • Status: Active Grant
First Claim
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1. A system comprising:

  • a first electrode and a second electrode, wherein at least one of the first electrode or the second electrode is implantably associated with a kidney of a subject;

    an electric field generator circuit coupled to the first electrode and the second electrode and configured to generate an electric field; and

    a controller circuit coupled to the electric field generator circuit and configured to control the electric field between the first and second electrodes, such that, through a process of electrophoresis, an electrophoretic gradient is produced to cause a net migration of a first constituent from a peritubular capillary of the kidney to a tubule associated with the peritubular capillary, wherein the first constituent is removed from the subject and a second constituent is maintained within a specified physiological range.

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