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Method and/or apparatus for determining codons

  • US 8,457,903 B1
  • Filed: 09/09/2011
  • Issued: 06/04/2013
  • Est. Priority Date: 01/19/1999
  • Status: Expired due to Term
First Claim
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1. A method, implemented at a computer system that includes one or more processors and system memory, for determining digital data representing a set of degenerate oligonucleotides, the method comprising:

  • displaying a first user interface on the computer system, the first user interface comprising one or more fields for inputting initial sequence data representing one or more polypeptides;

    receiving via the first user interface one or more data identifiers corresponding to the initial sequence data;

    displaying a second user interface on the computer system, the second user interface comprising one or more fields for selecting options for processing the initial sequence data;

    receiving via the second user interface one or more option identifiers corresponding to one or more selected options for processing the initial sequence data;

    backtranslating, on the computer system, said one or more polypeptides represented by the initial sequence data to create a set of backtranslated oligonucleotides;

    determining, on the computer system, a set of degenerate oligonucleotides from the set of backtranslated oligonucleotides, wherein members of the set of degenerate oligonucleotides are consistent with the selected options for processing the initial sequence data; and

    presenting digital data representing said set of degenerate oligonucleotides.

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