System and method for treating ischemic stroke

• US 8,460,312 B2
• Filed: 03/28/2011
• Issued: 06/11/2013
• Est. Priority Date: 09/10/2004
• Status: Active Grant

• Current Assignee: Penumbra, Inc.
• Original Assignee: Penumbra, Inc.
• Inventors: Bose, Arani, Gupta, Vikas, Hui, Delilah, Donohue, Sean
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): BACHMAN, LINDSEY MICHELE
• Application Number:
  US13/073,645
• Publication Number:
  US 20110172700A1
• Time in Patent Office: 806 Days
• Field of Search: 606/113, 606/114, 606/127, 606/128, 606/200
• US Class Current: 606/127
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22044 with a pointed tip
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector

Abstract

A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, a delivery and aspiration catheter, an aspiration pump, a thromboembolic receiver, and a thromboembolic separator.

Claims

1. A method for removing a thromboembolism from a blood vessel, said method comprising:

providing a device comprising a catheter having an axial lumen, a pusher element slidably disposed in the lumen of the catheter, and a thromboembolic receiver on a distal end of the pusher element, the receiver formed of a plurality of structural members arranged to form a sleeve having a central lumen, a first plurality of structural members comprising longitudinally extending struts, a second plurality of the structural members comprising v-shaped engaging elements, and a third set of structural members comprising a plurality of axially spaced-apart circumferential rings attached to the longitudinal struts, each of said v-shaped engaging elements being disposed between adjacent ones of the longitudinal struts and including a first leg extending into the central lumen from a first longitudinal strut and a second leg extending into the central lumen from a second, adjacent longitudinal strut, said first and second legs attached to one another within the central lumen to define a plurality of longitudinally oriented apexes extending into the central lumen, wherein at least a distal row and a proximal row of the v-shaped engaging elements are disposed between a distal circumferential ring and a proximal circumferential ring and each apex is unattached to any other structure within the central lumen;

positioning a distal end of the catheter adjacent to the thromboembolism in the blood vessel;

retracting the catheter relative to the pusher element to release the thromboembolic receiver from constraint so that the receiver expands to a cylindrical shape with a fully open end, wherein the open end of the expanded cylindrical thromboembolic receiver engages the thromboembolism; and

retracting the pusher element to remove the thromboembolism from the blood vessel.

2. A method as in claim 1, wherein the expanded thromboembolic receiver opens to engage an inner wall of the blood vessel.

3. A method as in claim 2, wherein the thromboembolic receiver is advanced distally over the thromboembolism.

4. A method for engaging a thromboembolic body within a blood vessel, the method comprising the steps of:

providing a receiver formed of a plurality of structural members arranged to form a sleeve having a central lumen, a first plurality of structural members comprising longitudinally extending struts, a second plurality of the structural members comprising v-shaped engaging elements, and a third set of structural members comprising a plurality of axially spaced-apart circumferential rings attached to the longitudinal struts, each of said v-shaped engaging elements being disposed between adjacent ones of the longitudinal struts and including a first leg extending into the central lumen from a first longitudinal strut and a second leg extending into the central lumen from a second, adjacent longitudinal strut, said first and second legs attached to one another within the central lumen to define a plurality of longitudinally oriented apexes extending into the central lumen, wherein at least a distal row and a proximal row of the v-shaped engaging elements are disposed between a distal circumferential ring and a proximal circumferential ring and each apex is unattached to any other structure within the central lumen; and

advancing the receiver over a body of thromboembolic material within a blood vessel, causing the body to be received into the central lumen, and causing the engaging elements to engage the body within the lumen.

5. The method of claim 4, further including the step of withdrawing the receiver, with the body in the central lumen, from the blood vessel.

6. The method of claim 4, wherein:

the providing step further provides a catheter, the receiver slidable within the catheter, wherein the receiver is radially expandable from a compressed position to an expanded position;

the method includes the steps of;

positioning the receiver, in the compressed position, within the catheter; and

positioning the catheter within the blood vessel in a position proximal of the body of thromboembolic material; and

the advancing step includes extending the receiver from the catheter.

7. The method of claim 6, further including the step of, following the advancing step, sliding a distal portion of the catheter against a proximal portion of the receiver to cause the receiver to exert pressure against the thromboembolic body in a radially inward direction.

8. The method of claim 4, further including the steps of:

positioning a sheath within the blood vessel, the sheath having an occlusion balloon thereon; and

occluding the blood vessel using the occlusion balloon.