Automatic adaptation of A-V delay and HR for heart failure using beat to beat measures
First Claim
Patent Images
1. A method of delivering pacing therapy to a heart, comprising:
- sensing one or more physiological parameters comprising autonomic tone, baroreflex, and chemoreflex;
adjusting, for each cardiac cycle of a plurality of cardiac cycles, one or both of an atrioventricular (A-V) timing interval and an atrial (A-A) timing interval to oppose beat-to-beat ventricular (V-V) variability so as to maintain relatively constant V-V intervals between ventricular beats of different cardiac cycles over the plurality of cardiac cycles, the adjusting based on the sensed physiological parameters; and
delivering the pacing therapy using the adjusted timing intervals.
0 Assignments
0 Petitions
Accused Products
Abstract
Methods and systems to modulate timing intervals for pacing therapy are described. For each cardiac cycle, one or both of an atrioventricular (A-V) timing interval and an atrial (A-A) timing interval are modulated to oppose beat-to-beat ventricular (V-V) timing variability. Pacing therapy is delivered using the modulated timing intervals.
-
Citations
20 Claims
-
1. A method of delivering pacing therapy to a heart, comprising:
-
sensing one or more physiological parameters comprising autonomic tone, baroreflex, and chemoreflex; adjusting, for each cardiac cycle of a plurality of cardiac cycles, one or both of an atrioventricular (A-V) timing interval and an atrial (A-A) timing interval to oppose beat-to-beat ventricular (V-V) variability so as to maintain relatively constant V-V intervals between ventricular beats of different cardiac cycles over the plurality of cardiac cycles, the adjusting based on the sensed physiological parameters; and delivering the pacing therapy using the adjusted timing intervals. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. A method of delivering pacing therapy to a heart, comprising:
-
sensing one or more physiological parameters; adjusting, for each cardiac cycle of a plurality of cardiac cycles, by determining an indicated pacing rate for one or both of an atrioventricular (A-V) timing interval and an atrial (A-A) timing interval to oppose beat-to-beat ventricular (V-V) variability so as to maintain relatively constant V-V intervals between ventricular beats of different cardiac cycles over the plurality of cardiac cycles, the adjusting based on the sensed physiological parameters; determining a respiration cycle phase; modulating the indicated pacing rate for the one or both of the atrioventricular (A-V) timing interval and the atrial (A-A) timing interval based on the respiration cycle phase to produce pacing that mimics respiratory sinus arrhythmia; and delivering the pacing therapy using the adjusted timing intervals. - View Dependent Claims (17, 18, 19, 20)
-
Specification