System and method for motion adaptive optimization for radiation therapy delivery
First Claim
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1. A method of delivering a radiation therapy treatment, the method comprising:
- generating a treatment plan for a patient, the treatment plan including a plurality of projections;
positioning the patient to receive radiation from a radiation source based on the treatment plan;
monitoring machine parameters during delivery of at least a portion of the plurality of projections in substantially real-time, the monitoring including analyzing information regarding the machine parameters and how the parameters affect dose delivered to the patient;
during delivery of at least a portion of the plurality of projections, calculating an accumulated radiation dose delivered to the patient in substantially real-time;
during delivery of at least a portion of the plurality of projections, optimizing at least a portion of the plurality of projections yet to be delivered to the patient in substantially real-time to incorporate the analyzed information from the monitored machine parameters and the accumulated radiation dose; and
delivering at least a portion of the plurality of projections yet to be delivered to the patient as optimized.
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Abstract
A system and method of optimizing delivery of a radiation therapy treatment. The system optimizes treatment delivery in real-time to take into account a variety of factors, such as patient anatomical and physiological changes (e.g., respiration and other movement, etc.), and machine configuration changes (e.g., beam output factors, couch error, leaf error, etc.).
153 Citations
30 Claims
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1. A method of delivering a radiation therapy treatment, the method comprising:
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generating a treatment plan for a patient, the treatment plan including a plurality of projections; positioning the patient to receive radiation from a radiation source based on the treatment plan; monitoring machine parameters during delivery of at least a portion of the plurality of projections in substantially real-time, the monitoring including analyzing information regarding the machine parameters and how the parameters affect dose delivered to the patient; during delivery of at least a portion of the plurality of projections, calculating an accumulated radiation dose delivered to the patient in substantially real-time; during delivery of at least a portion of the plurality of projections, optimizing at least a portion of the plurality of projections yet to be delivered to the patient in substantially real-time to incorporate the analyzed information from the monitored machine parameters and the accumulated radiation dose; and delivering at least a portion of the plurality of projections yet to be delivered to the patient as optimized. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 28)
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26. A method of delivering a radiation therapy treatment, the method comprising:
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generating a treatment plan for a patient, the treatment plan including a plurality of projections; positioning the patient to receive radiation from a radiation source based on the treatment plan; monitoring machine parameters during delivery of at least a portion of the plurality of projections in substantially real-time, the monitoring including analyzing information regarding the machine parameters and how the parameters affect dose delivered to the patient; monitoring changes to the patient during delivery of at least a portion of the plurality of projections in substantially real-time, the monitoring including analyzing information regarding the patient changes and how the changes affect dose delivered to the patient; during delivery of at least a portion of the plurality of projections, calculating an accumulated radiation dose delivered to the patient in substantially real-time; during delivery of at least a portion of the plurality of projections, optimizing at least a portion of the plurality of projections yet to be delivered to the patient in substantially real-time to incorporate the analyzed information from the monitored machine parameters, the monitored changes to the patient, and the accumulated radiation dose; and delivering at least a portion of the plurality of projections yet to be delivered to the patient as optimized. - View Dependent Claims (29)
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27. A method of delivering a radiation therapy treatment, the method comprising:
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generating a treatment plan for a patient, the treatment plan including a plurality of projections; positioning the patient to receive radiation from a radiation source based on the treatment plan; monitoring machine parameters during delivery of at least a portion of the plurality of projections in substantially real-time, the monitoring including analyzing information regarding the machine parameters and how the parameters affect dose delivered to the patient; during delivery of at least a portion of the plurality of projections, calculating an amount of accumulated radiation dose delivered to the patient in substantially real-time; during delivery of at least a portion of the plurality of projections, optimizing at least a portion of the plurality of projections yet to be delivered to the patient in substantially real-time to incorporate the analyzed information from the monitored machine parameters and the accumulated radiation dose, the optimizing including predicting machine parameters; and delivering at least a portion of the plurality of projections yet to be delivered to the patient as optimized. - View Dependent Claims (30)
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Specification