Stent-catheter assembly with a releasable connection for stent retention

• US 8,470,014 B2
• Filed: 08/14/2007
• Issued: 06/25/2013
• Est. Priority Date: 08/25/2004
• Status: Expired due to Fees

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Gale, David C., Kleine, Klaus, Abbate, Anthony, Huang, Bin, Atladottir, Svava M.
• Primary Examiner(s): ANDERSON, GREGORY A
• Application Number:
  US11/893,316
• Publication Number:
  US 20080033526A1
• Time in Patent Office: 2,142 Days
• Field of Search: 623 111- 112
• US Class Current: 623/1.11
• CPC Class Codes: A61F 2/9522 Means for mounting a stent or stent-graft onto or into a placement instrument
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/30448 using adhesives
• CPC Class Codes: A61F 2002/9583 Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2220/005 using adhesives

Abstract

Medical assemblies with a releasable connection and methods of constructing such medical assemblies are disclosed. The medical assemblies generally comprise a stent, a catheter assembly having catheter body a balloon, and a releasable connection between the stent and the catheter assembly that releases the stent from the catheter assembly in response to enlargement of the balloon or when the balloon has been enlarged to an expanded configuration.

Claims

1. A medical assembly comprising:

a nonbiodegradable stent;

a catheter comprising an expandable member having the stent positioned on the expandable member, the member capable of being expanded from a collapsed profile to an expanded profile; and

an apparatus for releasably connecting the stent to the member such that in response to the expansion of the member, the nonbiodegradable stent is detached from the member, wherein the apparatus comprises;

a cylindrical heating element that is placed between the stent and the expandable member when the stent is disposed around the expandable member, wherein the heating element applies heat to the stent and/or expandable member, wherein the cylindrical heating element is removable to allow releasably connecting the stent to the expandable member,

a pressurizing structure that is placed around the stent disposed around the expandable member to apply inward radial pressure to the stent in conjunction with heat from the heating element to releasably connect the stent to the expandable member.

2. A medical assembly comprising:

a nonbiodegradable stent;

a catheter assembly comprising a catheter body and a balloon having the stent positioned on the balloon, the balloon having a deflated configuration and capable of being enlarged to an expanded configuration; and

a releasable connection between the stent and the catheter body, wherein the releasable connection retains the stent on the catheter body, wherein the releasable connection is formed in a region of the catheter body axially distal or proximal to the balloon, and the releasable connection releases the stent from the catheter body in response to enlargement of the balloon or when the balloon has been enlarged to an expanded configuration, wherein the releasable connection is located between an inner surface of the stent and an outer surface of the catheter body.

3. The assembly of claim 2, wherein the releasable connection releases off of the stent.

4. The assembly of claim 2, wherein the releasable connection releases off of the catheter.

5. The assembly of claim 2, further comprising an intermediary material between the releasable connection and the stent, the releasable connection and the catheter body, or the combination thereof.

6. The assembly of claim 5, wherein the intermediary material is a coating.

7. The assembly of claim 5, wherein the releasable connection releases off of the intermediary material.

8. A method for constructing a medical assembly comprising:

placing a nonbiodegradable stent over a balloon of a catheter assembly; and

forming a releasable connection between the stent and the catheter assembly such that in response to the enlargement of the balloon or when the balloon has been enlarged to an expanded configuration, the stent is detached from the catheter assembly, wherein the forming a releasable connection comprises;

depositing an adhesive material on the catheter assembly and/or an inner side of the stent, the adhesive material being of the type that allows for the detachment of the stent from the catheter assembly in response to the enlargement of the balloon or when the balloon has been enlarged to an expanded configuration;

applying pressure to the stent to allow the adhesive material to contact the stent and catheter assembly to form the releasable connection; and

applying heat to assist the pressure to form the releasable connection formed by the adhesive material.

9. The method of claim 8, wherein the balloon is in a collapsed configuration when the releasable connection is formed between the stent and the catheter assembly.

10. The method of claim 8, wherein the releasable connection disengages from the stent.

11. The method of claim 8, wherein the releasable connection disengages from the balloon.

12. The method of claim 8, wherein the releasable connection disengages from the catheter assembly in a region outside of the balloon.

13. The method of claim 8, wherein the releasable connection is configured to break in parts to disengage the stent from the balloon.

14. A method for constructing a medical assembly comprising:

placing a nonbiodegradable stent over a balloon of a catheter assembly; and

forming a releasable connection between the stent and the catheter assembly such that in response to the enlargement of the balloon or when the balloon has been enlarged to an expanded configuration, the stent is detached from the catheter assembly,

wherein the method of forming the releasable connection comprises;

applying a solvent to an inner surface of the stent and/or an outer surface of the catheter assembly prior to

placing the stent over the balloon wherein the stent has a reduced diameter prior to placing the stent over the balloon, the reduced diameter is a diameter for purposes of properly delivering the stent in a lumen within a mammal followed by

removing the solvent, wherein the releasable connection is formed by solvent welding to form a fused union.

15. The method of claim 14, wherein the stent includes a material on an inner surface thereof and/or the catheter assembly includes a material on the outer surface thereof, and wherein the solvent is applied to the material on the stent and/or the material on the catheter assembly.

16. The method of claim 15, wherein the releasable connection disengages from the material on the stent, the material on the balloon, the material on the catheter assembly in a region outside of the balloon, or a combination thereof.

17. The method of claim 14, wherein the stent includes a material on an inner surface thereof and/or the catheter assembly includes a material on the outer surface thereof, and wherein the solvent is applied to the material on the stent and/or the material on the catheter assembly.

18. The method of claim 17, wherein the releasable connection disengages from the material on the stent, the material on the balloon, the material on the catheter assembly in a region outside of the balloon, or a combination thereof.

19. A method for constructing a medical assembly comprising:

placing a nonbiodegradable stent over a balloon of a catheter assembly; and

forming a releasable connection between the stent and the catheter assembly such that in response to the enlargement of the balloon or when the balloon has been enlarged to an expanded configuration, the stent is detached from the catheter assembly, wherein the forming the releasable connection comprises;

injecting a melted material between the catheter assembly and the stent.

20. A method for constructing a medical assembly comprising:

placing a nonbiodegradable stent over a balloon of a catheter assembly; and

forming a releasable connection between the stent and the catheter assembly such that in response to the enlargement of the balloon or when the balloon has been enlarged to an expanded configuration, the stent is detached from the catheter assembly, wherein the forming the releasable connection comprises;

placing a heating element between the stent and the catheter assembly;

applying heat to connect the stent to the catheter assembly.

21. The method of claim 20, wherein the stent is made completely or in-part from a polymeric material.

22. The method of claim 20, wherein the stent includes a material deposited on an inner surface thereof and/or the catheter assembly includes a material deposited on an outer surface thereof, such that application of heat to the material on the stent and/or the material on the catheter assembly allows for connection of the stent to the catheter assembly.

23. The method of claim 22, wherein the material on the stent and/or the catheter assembly has a lower melting temperature than the stent and the catheter assembly.

24. The method of claim 22, wherein the material on the stent and/or the catheter assembly has a higher melting temperature than the stent and the assembly.