Implanted bronchial isolation devices and methods
First Claim
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1. A flow control device suitable for implanting in a bronchial passageway, comprising:
- a valve element comprising a first lip and a second lip, wherein the first and second lips are configured to transition the valve element between an open configuration that permits air flow in an expiratory direction and a closed configuration that blocks air flow in the inspiratory direction, wherein the first and second lips are configured to be substantially parallel to maintain an opening in a default state such that the first and second lips move away from one another to increase the size of the opening to a size larger than the size of the opening in the default state when exposed to air flow in the expiratory direction and the valve element transitions toward the closed configuration when exposed to air flow in the inspiratory direction;
wherein the valve element is in the default state when there is no pressure differential across the valve.
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Abstract
Disclosed are methods and devices for regulating fluid flow to and from a region of a patient'"'"'s lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.
302 Citations
13 Claims
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1. A flow control device suitable for implanting in a bronchial passageway, comprising:
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a valve element comprising a first lip and a second lip, wherein the first and second lips are configured to transition the valve element between an open configuration that permits air flow in an expiratory direction and a closed configuration that blocks air flow in the inspiratory direction, wherein the first and second lips are configured to be substantially parallel to maintain an opening in a default state such that the first and second lips move away from one another to increase the size of the opening to a size larger than the size of the opening in the default state when exposed to air flow in the expiratory direction and the valve element transitions toward the closed configuration when exposed to air flow in the inspiratory direction; wherein the valve element is in the default state when there is no pressure differential across the valve. - View Dependent Claims (2, 3)
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4. A flow control device suitable for implanting in a bronchial passageway, comprising:
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a valve defining a variable-sized mouth through which air can flow through the valve to regulate air flow when implanted in the bronchial passageway, wherein the mouth increases in size in response to air flow in a first direction and the mouth decreases in size in response to air flow in a second direction and wherein the valve includes coaptation regions comprising a first lip and a second lip that are connected at opposed corners that are parallel and define the mouth therebetween, the mouth being open when the coaptation regions are at least partially spaced apart from one another, wherein the first and second lips are at least partially spaced apart in a parallel fashion to keep the mouth open when exposed to no air flow, wherein the coaptation regions move away from one another to increase the size of the mouth to a size larger than the size of the mouth when exposed to no air flow in response to air flow in the first direction and move toward one another to decrease the size of the mouth in response to air flow in the second direction. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11)
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12. An air flow control device suitable for implanting in a bronchial passageway, comprising:
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a frame configured to retain the flow control device within the bronchial passageway; a seal coupled to the frame, the seal configured to seal against internal walls of the bronchial passageway; and a valve coupled to the frame, the valve having lips that define a variable-sized mouth through which air can flow through the valve, wherein the lips are parallel and are at least partially spaced apart to define an open mouth when the valve is exposed to no air flow, and wherein the lips move away from one another to increase the size of the mouth to a size larger than the size of the mouth when the valve is exposed to no air flow in response to air flow in a first direction and the lips move toward one another to decrease the size of the mouth in response to air flow in a second direction. - View Dependent Claims (13)
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Specification