Topical composition containing galvanic particulates

• US 8,475,689 B2
• Filed: 10/31/2006
• Issued: 07/02/2013
• Est. Priority Date: 06/30/2003
• Status: Active Grant

• Current Assignee: Johnson & Johnson Consumer Inc. (Johnson & Johnson)
• Original Assignee: Johnson & Johnson Consumer Companies Incorporated (Johnson & Johnson)
• Inventors: Sun, Ying, Liu, Jue-Chen, Wu, Jeffrey M., Hauschild, James E.
• Primary Examiner(s): Pyon, Harold
• Assistant Examiner(s): Diggs, Tanisha
• Application Number:
  US11/590,380
• Publication Number:
  US 20070060862A1
• Time in Patent Office: 2,436 Days
• Field of Search: 252/500, 252/512, 252/519.5, 252/519.51, 424/401, 424/490, 424/630, 424/641, 427/58
• US Class Current: 252/519.51
• CPC Class Codes: A61K 2800/28 Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
• CPC Class Codes: A61K 2800/83 Electrophoresis; Electrodes; Electrolytic phenomena
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/20 Halogens; Compounds thereof
• CPC Class Codes: A61K 8/27 Zinc; Compounds thereof
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61K 8/368 with carboxyl groups directly bound to carbon atoms of aromatic rings
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
• CPC Class Codes: A61N 1/0436 Material of the electrode
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir
• CPC Class Codes: A61N 1/0492 Patch electrodes A61N1/0412, A61N1/0428 take precedence
• CPC Class Codes: A61N 1/205 for promoting a biological process
• CPC Class Codes: A61N 1/30 Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
• CPC Class Codes: A61N 1/303 Constructional details electrodes for external use A61N1/0428
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428
• CPC Class Codes: A61Q 19/008 Preparations for oily skin
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations

Abstract

A topical composition containing galvanic particulates consisting of a first conductive material that is zinc and a second conductive material that is copper is provided.

Claims

1. A topical composition comprising particulates consisting of a first conductive material that is zinc and a second conductive material that is copper, wherein average particle size of said particulates is from about 1 micrometer to about 2 millimeters, and wherein said first conductive material and said second conductive material form a galvanic pair and generate electric current upon topical application, said particulates consisting of a powder of zinc that is partially coated with copper, and said composition comprises a semi-solid dosage form selected from the group consisting of a gel, a hydrogel, a water-in-oil emulsion, an oil-in-water emulsion, a cream, a lotion, an ointment, a multi-emulsion, and a liposome.

2. A topical composition of claim 1 further comprising an active agent.

3. A topical composition of claim 2, wherein the active agent is an anti-acne agent.

4. A topical composition of claim 3, wherein the anti-acne agent is selected from the group consisting of salicylic acid, benzoyl peroxide, retinoic acid and retinol.