Method and apparatus for storage and dispensing of pharmaceutical products in unit doses or administration units

• US 8,478,441 B2
• Filed: 03/17/2009
• Issued: 07/02/2013
• Est. Priority Date: 03/19/2008
• Status: Active Grant

• Current Assignee: Deenova Srl (Santa Lucia Pharma Apps SRL)
• Original Assignee: Ingegneria Biomedica Santa Lucia S.p.A. (Althea Group SpA)
• Inventors: Liguori, Pierangelo, Pavesi, Giorgio, Rudello, Fulvio
• Primary Examiner(s): COLLINS, MICHAEL
• Application Number:
  US12/933,187
• Publication Number:
  US 20110017764A1
• Time in Patent Office: 1,568 Days
• Field of Search: 700/232, 700/236, 700/242, 700/243
• US Class Current: 700/243
• CPC Class Codes: G07F 11/165 using xyz-picker or multi-dimensional article picking arrangements
• CPC Class Codes: G07F 11/1657 the picking arrangements using suction
• CPC Class Codes: G07F 11/64 in which the articles are individually suspended from stationary supports
• CPC Class Codes: G07F 17/0092 for assembling and dispensing of pharmaceutical articles medical dispensers for private use, A61J7/00

Abstract

A method and automated apparatus (1) for dispensing pharmaceutical products in unit doses or administration units wherein the unit doses (2) suitably arranged and/or separated within the apparatus (1) can be dispensed into the compartments (5) of an associated cart (4), to fill patient-specific medication prescriptions for patients of a ward. A telescopic manipulator unit (6, 106, 206) has elements (16) adapted to select and pick up the doses required to fill patient-specific medication prescriptions from a matrix (10) of unit doses (2) and elements (7, 107) for coupled interaction with the compartments (5) to directly release the picked up doses (2) therein.

Claims

1. An automated apparatus configured for storage and dispensing of pharmaceutical products, said pharmaceutical products being divided into unit doses or administration units, and suitably arranged in a matrix of unit doses, comprising:

a closed structure configured to hold the unit doses or the administration units so as to be protected from manual handling;

a detachable cart joined to an outside of the closed structure; and

a manipulator unit inside the closed structure, which is designed for;

a) selecting and picking up the unit doses or administration units required to fill patient-specific prescriptions from said matrix, and

b) loading compartments/drawers of the cart with said unit doses or said administration units so selected and picked up, said compartments/drawers facing toward an inside of the closed structure and being loaded when the closed structure and the cart are attached,

wherein the manipulator unit comprises means for coupling configured for opening and closing the compartments/drawers of a means for introducing one or more of the unit doses or administration units picked up from the matrix,

said means for coupling being connected to the manipulator unit to cause the compartments/drawers associated with the cart to be grasped and opened or closed.

2. The apparatus as claimed in claim 1, wherein the loading process is carried out once such that one or more of the doses or the administration units that fill the medicament prescription are selected or introduced in the compartments/drawers one by one as they are selected.

3. The apparatus as claimed in claim 1, wherein the manipulator unit includes means for introducing one or more the unit doses or the administration units picked up from the matrix.

4. The apparatus as claimed in claim 1, wherein the manipulator unit has intermediate support means for temporarily holding the selected and picked up doses or administration units until the corresponding drawer/compartment is opened.

5. The apparatus as claimed in claim 1, wherein said manipulator unit has a telescopic arm which extends along guides to reach even the innermost doses or administration units on rods.

6. The apparatus as claimed in claim 5, wherein said telescopic arm has a suction cup gripper for grasping the unit doses or administration units.

7. The apparatus as claimed in claim 5, said telescopic arm has means for reading a barcode of the dose or the administration unit to be picked up and/or handled.

8. The apparatus as claimed in claim 1, wherein said manipulator unit has means for allowing displacement along at least two vertical and transverse Cartesian axes, to cover a whole width of a panel or the matrix.

9. The apparatus as claimed in claim 1, wherein said unit doses or said administration units are supported by substantially horizontal pegs or rods carried by a panel or the matrix having special hanging loops;

said panel, rods and respective doses or administration units, wholly contained in the closed structure of the apparatus are protected from undesired handling.

10. The apparatus as claimed in claim 6, wherein the manipulator unit has a spout which is adapted to be coaxial and aligned with corresponding pegs with which the spout comes in contact.

11. The apparatus as claimed in claim 10, wherein said spout and said pegs have helical threads, for axial forward displacement of the dose or the administration unit received in a groove of said threads, upon rotation of the spout.

12. The apparatus as claimed in claim 10, wherein said suction cup gripper is configured to move the dose from the peg to the spout and then from the spout to a support or a retainer means;

once the retainer is retracted, the doses or administration units so picked up are released into the underlying compartment using a tilting chute which allows proper routing of the doses or administration units to their final destination.

13. The apparatus as claimed in claim 1, wherein the manipulator unit includes a chute that forms, in combination with a corresponding retainer an intermediate holder for the unit doses or administration units that have been picked up.

14. The apparatus as claimed in claim 1, wherein said manipulator unit has integral means for gripping which are adapted to grasp the doses or administration units temporarily held by a retainer of the matrix and then release the doses or administration units onto a tilting chute which allows proper routing of the doses or administration units to their final destination in their corresponding drawer.

15. The apparatus as claimed in claim 1, wherein the apparatus is modular and expansible, by addition of further sections containing matrices of pegs, in response to requirements of wards having different pharmaceutical consumption parameters.

16. The apparatus as claimed in claim 1, wherein the manipulator unit has a spout which is adapted to be coaxial and aligned with the corresponding pegs with which the spout comes in contact.

17. A method for dispensing pharmaceutical products in unit doses or administration units, comprising:

selecting and picking up the unit doses or administration units required to fill together patient-specific prescriptions from a dose matrix; and

interacting with containers or drawers of an associated cart loaded with the picked up doses or administration units, said picked up doses or administration units being loaded into compartment after selection of the doses or administration units that fill the prescription or one by one as the doses or administration units are selected,

wherein

a closed structure is configured to hold the unit doses or the administration units so as to be protected from manual handling,

a detachable cart is joined to an outside of the closed structure,

said containers or drawers face toward an inside of the closed structure and being loaded when the closed structure and the cart are attached,

the manipulator unit comprises means for coupling configured for opening and closing the containers or drawers of a means for introducing one or more of the unit doses or administration units picked up from the matrix, and

means for coupling being connected to the manipulator unit to cause the containers or drawers associated with the cart to be grasped and opened or closed.

18. The method as claimed in claim 17, further including picking up unit doses or administration units using a suction cup on a telescopic arm of the manipulator unit that is allowed to move along the three cartesian axes.

19. The method as claimed in claim 17, further comprising selecting the doses or administration units using a barcode reader for reading a barcode on the dose or administration unit.

20. The method as claimed in claim 17, further including replenishing the matrix using a same selection and pick-up means.

21. The method as claimed in claim 20, the administration units or administration units are replenished manually in a dedicated area or a loading receptacle formed from a panel equipped with bars, which slides out to be loaded by an operator with the required unit doses or administration units that will be later rearranged by the manipulator unit;

the operator is not required particular positioning of the unit doses or administration units;

the operator can place the doses randomly so that a bar code reader is able to read—

via a bar code—

each dose or administration unit and to place each dose or administration unit in the desired position as managed by software.

22. The method as claimed in claim 17, wherein the method allows automated sequential preparation of medicaments for multiple patients, one drawer/compartment of the cart being assigned to each patient.

23. A computer program having computer program code for carrying out the method of claim 17 when said program is run on a computer, the computer program being embodied in a non-transitory medium.

24. The program as claimed in claim 23, wherein:

a) the program allows medicament regime design directly from prescription lists;

b) the program allows management of pegs even in multi-drug mode, to allow loading of one peg with unit doses of different low-rotation medicaments, the program being able to ascertain the position of each medicament dose;

c) the program allows medicament delivery as needed;

d) the program manages mission priority;

e) the program manages inventory;

f) the program optimizes dose shelf life;

g) the program controls internal ventilation/conditioning;

also the program records temperatures for documentation and certification purposes;

h) the program controls stock consistency and congruence; and

i) the program allows integrated management of all configuration parameters.

25. The computer program as claimed in claim 23, wherein the computer program is stored on computer readable media.