Drug delivery pump drive using a shaped memory alloy wire

• US 8,480,633 B2
• Filed: 04/30/2012
• Issued: 07/09/2013
• Est. Priority Date: 05/15/2008
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Roe, Steven N.
• Primary Examiner(s): SCHMIDT, EMILY LOUISE
• Application Number:
  US13/460,087
• Publication Number:
  US 20120230845A1
• Time in Patent Office: 435 Days
• Field of Search: 604/207, 604/208, 604/211, 74/25
• US Class Current: 604/207
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: F03G 7/065 using a shape memory element
• CPC Class Codes: Y10T 74/18056 Rotary to or from reciprocating or oscillating

Abstract

A pump drive and a method thereof to dispense a liquid drug from a container having a plunger piston are disclosed. The pump drive provides a unidirectional clutch provided about a rotational axis which supports centrally a wheel. The clutch has an inner race operably connected to the plunger piston, wherein the clutch is configured to rotate both the inner race about the axis in unison with rotation of the wheel in only a first direction to advance the plunger piston, and to let the wheel rotate relative to the inner race about the axis in a second direction opposite to the first direction without advancing the piston plunger. The drive in one embodiment includes at least one shape memory alloy wire which when excited rotates the wheel in the first rotational direction to advance the piston plunger and dispense the liquid drug from the container.

Claims

1. A pump drive used to dispense a liquid drug from a container having a plunger piston, said pump drive comprising:

a lead screw having a rotational axis and being operably connected to the plunger piston, wherein rotation of the lead screw about the rotational axis advances the piston plunger in a dispensing direction which dispenses the liquid drug from the container;

a wheel;

a unidirectional clutch provided about the rotational axis and supporting centrally the wheel, the unidirectional clutch having an inner race connected centrally to the lead screw, wherein the unidirectional clutch is configured to rotate both the inner race and lead screw about the rotational axis in unison with rotation of the wheel in only a first rotational direction, and to let the wheel rotate relative to the inner race without rotating the lead screw about the rotational axis in a second rotational direction opposite to the first rotational direction;

a spring to rotate the wheel in the second rotational direction; and

a plurality of shape memory alloy wires to provide the motor force when excited to rotate the wheel in at least the first rotational direction;

wherein the spring is connected directly to the wheel and the plurality of shape memory alloy wires are also connected directly to the wheel.

2. The pump drive according to claim 1, wherein the plurality of shape memory alloy wires are each mounted laterally to the wheel and wherein the spring is mounted laterally to the wheel and acting in opposition to the plurality of shape memory alloy wires to provide the motor force to rotate the wheel in the second rotational direction.

3. The pump drive according to claim 1, wherein the shape memory alloy wire is wrapped around at least half the circumference of the wheel.

4. A method of dispensing a liquid drug from a container having a plunger piston, said method comprises:

providing a lead screw having a rotational axis and operably connecting the lead screw to the plunger piston wherein rotation of the lead screw about the rotational axis advances the piston plunger in a dispensing direction which dispenses the liquid drug from the container;

providing a wheel;

providing a unidirectional clutch to support the wheel about the rotational axis;

connecting an inner race of the unidirectional clutch centrally to the lead screw, wherein the unidirectional clutch is configured to rotate both the inner race and lead screw about the rotational axis in unison with rotation of the wheel only in a first rotational direction, and to let the wheel rotation relative to the inner race without rotating the lead screw about the rotational axis in a second rotational direction opposite to the first rotational direction;

providing a plurality of shape memory alloy wires which when excited provides a motor force to rotate the wheel in at least the first rotational direction;

providing a spring to rotate the wheel in the second rotational direction; and

exciting the plurality of shape memory alloy wires;

wherein the spring is connected directly to the wheel and the shape memory alloy wires are also connected directly to the wheel.