Automated therapy system and method

• US 8,480,648 B2
• Filed: 01/19/2012
• Issued: 07/09/2013
• Est. Priority Date: 04/05/2007
• Status: Active Grant

• Current Assignee: Theranova, Llc
• Original Assignee: Velomedix, Inc.
• Inventors: Burnett, Daniel Rogers, Hall, Gregory, Hermanson, Christopher, Rajguru, Amit
• Primary Examiner(s): Stigell, Theodore
• Assistant Examiner(s): Zhang, Jenna
• Application Number:
  US13/354,210
• Publication Number:
  US 20120116487A1
• Time in Patent Office: 537 Days
• Field of Search: 604/503, 604/508, 604/66
• US Class Current: 604/503
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/068 using impedance sensors
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/207 Sensing devices adapted to collect urine
• CPC Class Codes: A61B 5/208 adapted to determine urine quantity, e.g. flow, volume
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61F 2007/0022 Abdomen
• CPC Class Codes: A61F 2007/0063 for cooling
• CPC Class Codes: A61F 2007/0093 programmed
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 2025/0166 Sensors, electrodes or the like for guiding the catheter to a target zone, e.g. image guided or magnetically guided
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/10 Electroencephalographic signals
• CPC Class Codes: A61M 2230/202 partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2230/205 : partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/208 : pH-value
• CPC Class Codes: A61M 2230/65 : Impedance, e.g. conductivity, capacity
• CPC Class Codes: A61M 5/142 : Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

Claims

1. A method of inducing and reversing therapeutic hyperthermia in a patient, the method comprising:

infusing a therapeutic agent into a peritoneal cavity of the patient to induce or reverse therapeutic hyperthermia;

monitoring a patient parameter with a sensor to generate a sensor signal;

providing the sensor signal to a controller; and

adjusting flow of the therapeutic agent to the peritoneal cavity of the patient with the controller based on the sensor signal without removing the therapeutic agent from the patient.

2. The method of claim 1 wherein the therapeutic agent is infused into the patient with a peritoneal catheter.

3. The method of claim 1 wherein the patient parameter comprises intraperitoneal pressure.

4. The method of claim 1 wherein the patient parameter comprises intrathoracic pressure.

5. The method of claim 1 wherein the patient parameter comprises intracranial pressure.

6. The method of claim 1 wherein the infusing step comprises a peritoneal lavage.

7. The method of claim 1 wherein the adjusting step is performed after the infusing step.

8. A system configured to induce and reverse therapeutic hypothermia or hyperthermia in a patient, the system comprising:

a fluid source having a therapeutic agent;

a peritoneal catheter coupled to the fluid source, the peritoneal catheter configured to infuse the therapeutic agent into a peritoneal cavity of the patient;

a sensor configured to monitor a patient parameter to generate a sensor signal; and

a controller in communication with the sensor, the controller configured to adjust flow of the therapeutic agent from the peritoneal catheter into the peritoneal cavity based on the sensor signal to induce or reverse therapeutic hypothermia or hyperthermia in the patient without removing the therapeutic agent from the patient.

9. The system of claim 8 wherein the sensor is disposed in the peritoneal catheter.

10. The system of claim 8 wherein the sensor is separate from the peritoneal catheter.

11. The system of claim 8 wherein the sensor comprises a pH sensor.

12. The system of claim 8 wherein the sensor comprises a pressure sensor.

13. The system of claim 12 wherein the sensor comprises an intracranial pressure sensor.

14. The system of claim 12 wherein the sensor comprises an intraperitoneal pressure sensor.

15. The system of claim 8 wherein the sensor comprises a blood pressure sensor.

16. The system of claim 8 wherein the therapeutic agent comprises a chilled medium.

17. The system of claim 8 wherein the controller is configured to automatically adjust flow based on the sensor signal.